| 1. Ronde | 14.08.2021 | Energie Cottbus [A-jun] | - | Chemnitzer FC [A-jun] | 2:0 | ||||
| 2. Ronde | 21.08.2021 | Chemnitzer FC [A-jun] | - | Hamburger SV [A-jun] | 1:1 | ||||
| 3. Ronde | 11.09.2021 | FC St. Pauli [A-jun] | - | Chemnitzer FC [A-jun] | 3:0 | ||||
| 4. Ronde | 18.09.2021 | Chemnitzer FC [A-jun] | - | FC Carl Zeiss Jena [A-jun] | 1:1 | ||||
| 5. Ronde | 26.09.2021 | VfL Osnabrück [A-jun] | - | Chemnitzer FC [A-jun] | 1:0 | ||||
| 7. Ronde | 16.10.2021 | RB Leipzig [A-jun] | - | Chemnitzer FC [A-jun] | 0:1 | ||||
| 10. Ronde | 01.12.2021 | Dynamo Dresden [A-jun] | - | Chemnitzer FC [A-jun] | 2:0 | ||||
| 12. Ronde | 04.12.2021 | Hallescher FC [A-jun] | - | Chemnitzer FC [A-jun] | 1:1 |
Kosovo