| 3. Ronde | 21.08.2021 | Greenock Morton FC | - | Queen Of The South | 2:3 | ||||
| 4. Ronde | 28.08.2021 | Queen Of The South | - | Hamilton Academical | 1:2 | ||||
| 5. Ronde | 11.09.2021 | Raith Rovers | - | Queen Of The South | 0:1 | ||||
| 6. Ronde | 18.09.2021 | Queen Of The South | - | Arbroath FC | 0:2 | ||||
| 7. Ronde | 25.09.2021 | Inverness CT | - | Queen Of The South | 2:1 | ||||
| 8. Ronde | 02.10.2021 | Queen Of The South | - | Dunfermline Athletic | 1:0 | ||||
| 9. Ronde | 16.10.2021 | Ayr United | - | Queen Of The South | 2:1 | ||||
| 10. Ronde | 23.10.2021 | Queen Of The South | - | Greenock Morton FC | 0:0 | ||||
| 11. Ronde | 26.10.2021 | Hamilton Academical | - | Queen Of The South | 1:0 | ||||
| 12. Ronde | 30.10.2021 | Kilmarnock FC | - | Queen Of The South | 4:0 | ||||
| 13. Ronde | 06.11.2021 | Queen Of The South | - | Raith Rovers | 1:1 | ||||
| 14. Ronde | 13.11.2021 | Arbroath FC | - | Queen Of The South | 1:1 | ||||
| 15. Ronde | 19.11.2021 | Queen Of The South | - | Inverness CT | 1:2 | ||||
| 16. Ronde | 04.12.2021 | Queen Of The South | - | Partick Thistle | 0:0 | ||||
| 17. Ronde | 11.12.2021 | Dunfermline Athletic | - | Queen Of The South | 3:3 | ||||
| 18. Ronde | 18.12.2021 | Queen Of The South | - | Ayr United | 3:0 |
Engeland