| 1. Ronde | 06.08.2005 | Leyton Orient | - | Macclesfield Town | 2:1 | ||||
| 7. Ronde | 03.09.2005 | Leyton Orient | - | Bristol Rovers | 2:3 | ||||
| 8. Ronde | 10.09.2005 | Barnet FC | - | Leyton Orient | 2:3 | ||||
| 9. Ronde | 17.09.2005 | Leyton Orient | - | Wrexham AFC | 1:1 | ||||
| 10. Ronde | 24.09.2005 | Carlisle United | - | Leyton Orient | 2:3 | ||||
| 13. Ronde | 08.10.2005 | Stockport County | - | Leyton Orient | 1:1 | ||||
| 14. Ronde | 15.10.2005 | Leyton Orient | - | Lincoln City | 1:1 | ||||
| 20. Ronde | 06.12.2005 | Leyton Orient | - | Chester City | 0:1 | ||||
| 21. Ronde | 10.12.2005 | Leyton Orient | - | Bury FC | 0:1 | ||||
| 23. Ronde | 26.12.2005 | Leyton Orient | - | Rushden & Diamonds FC | 5:1 | ||||
| 24. Ronde | 29.12.2005 | Wycombe Wanderers | - | Leyton Orient | 4:2 | ||||
| 28. Ronde | 14.01.2006 | Leyton Orient | - | Northampton Town | 1:2 |
Noord-Ierland