| 3. Ronde | 19.02.2022 | Newell's Old Boys II | - | River Plate II | 1:2 | ||||
| 8. Ronde | 04.04.2022 | Newell's Old Boys II | - | Platense II | 1:2 | ||||
| 9. Ronde | 08.04.2022 | Unión de Santa Fe II | - | Newell's Old Boys II | 1:1 | ||||
| 10. Ronde | 13.04.2022 | Newell's Old Boys II | - | Patronato de Paraná II | 1:0 | ||||
| 11. Ronde | 19.04.2022 | Newell's Old Boys II | - | Banfield II | 1:0 | ||||
| 12. Ronde | 26.04.2022 | Racing Club II | - | Newell's Old Boys II | 1:1 | ||||
| 13. Ronde | 30.04.2022 | Newell's Old Boys II | - | San Lorenzo II | 0:3 | ||||
| 14. Ronde | 05.05.2022 | Gimnasia de La Plata II | - | Newell's Old Boys II | 1:3 |  |
Argentinië