| 5. Ronde | 26.09.2021 | Taranto FC | - | Latina Calcio | 2:0 |  |
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| 6. Ronde | 29.09.2021 | Taranto FC | - | Monterosi FC | 0:0 | ||||
| 8. Ronde | 10.10.2021 | Taranto FC | - | Vibonese Calcio | 0:0 | ||||
| 9. Ronde | 17.10.2021 | US Catanzaro | - | Taranto FC | 3:0 | |
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| 10. Ronde | 20.10.2021 | Taranto FC | - | Fidelis Andria | 2:1 | ||||
| 12. Ronde | 30.10.2021 | Taranto FC | - | Potenza | 2:1 | ||||
| 13. Ronde | 06.11.2021 | US Avellino | - | Taranto FC | 2:1 | ||||
| 14. Ronde | 14.11.2021 | SS Monopoli 1966 | - | Taranto FC | 2:0 | ||||
| 15. Ronde | 21.11.2021 | Taranto FC | - | Calcio Catania | geannuleerd | ||||
| 16. Ronde | 29.11.2021 | Juve Stabia | - | Taranto FC | 3:2 | ||||
| 17. Ronde | 05.12.2021 | Taranto FC | - | ACR Messina | 0:0 | ||||
| 18. Ronde | 12.12.2021 | SSC Bari | - | Taranto FC | 3:1 | |
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| 25. Ronde | 06.02.2022 | Monterosi FC | - | Taranto FC | 2:1 | ||||
| 26. Ronde | 12.02.2022 | Taranto FC | - | Virtus Francavilla | 0:0 | ||||
| 29. Ronde | 26.02.2022 | Fidelis Andria | - | Taranto FC | 3:0 | ||||
| 32. Ronde | 16.03.2022 | Taranto FC | - | US Avellino | 0:1 | ||||
| 22. Ronde | 30.03.2022 | Palermo FC | - | Taranto FC | 5:2 | ||||
| 35. Ronde | 03.04.2022 | Taranto FC | - | Juve Stabia | 0:0 | |
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| 37. Ronde | 16.04.2022 | Taranto FC | - | SSC Bari | 0:0 |  |
Italië