| 1. Ronde | 14.08.2021 | FC St. Pauli [A-jun] | - | Holstein Kiel [A-jun] | 3:6 |  |
|||
| 2. Ronde | 21.08.2021 | RB Leipzig [A-jun] | - | FC St. Pauli [A-jun] | 2:2 | ||||
| 3. Ronde | 11.09.2021 | FC St. Pauli [A-jun] | - | Chemnitzer FC [A-jun] | 3:0 | |
|||
| 4. Ronde | 17.09.2021 | Eimsbütteler TV [A-jun] | - | FC St. Pauli [A-jun] | 1:1 | ||||
| 5. Ronde | 25.09.2021 | FC St. Pauli [A-jun] | - | Dynamo Dresden [A-jun] | 0:1 | ||||
| 7. Ronde | 16.10.2021 | FC St. Pauli [A-jun] | - | Hallescher FC [A-jun] | 3:2 |  |
|||
| 8. Ronde | 23.10.2021 | VfL Wolfsburg [A-jun] | - | FC St. Pauli [A-jun] | 2:2 | ||||
| 9. Ronde | 30.10.2021 | FC St. Pauli [A-jun] | - | Werder Bremen [A-jun] | 0:1 | ||||
| 12. Ronde | 05.02.2022 | 1. FC Union Berlin [A-jun] | - | FC St. Pauli [A-jun] | 2:1 | ||||
| 11. Ronde | 12.02.2022 | FC St. Pauli [A-jun] | - | 1. FC Magdeburg [A-jun] | 2:1 | ||||
| 15. Ronde | 05.03.2022 | FC St. Pauli [A-jun] | - | Energie Cottbus [A-jun] | 0:2 | |
|||
| 13. Ronde | 17.03.2022 | FC St. Pauli [A-jun] | - | Hannover 96 [A-jun] | 2:1 | ||||
| 16. Ronde | 02.04.2022 | Hamburger SV [A-jun] | - | FC St. Pauli [A-jun] | 2:1 |  |
Duitsland