| 23. Ronde | 18.12.2021 | Middlesbrough FC | - | AFC Bournemouth | 1:0 |  |
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| 24. Ronde | 26.12.2021 | Middlesbrough FC | - | Nottingham Forest | 2:0 | ||||
| 27. Ronde | 15.01.2022 | Middlesbrough FC | - | Reading FC | 2:1 | ||||
| 28. Ronde | 24.01.2022 | Blackburn Rovers | - | Middlesbrough FC | 1:0 | |
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| 29. Ronde | 29.01.2022 | Middlesbrough FC | - | Coventry City | 1:0 | |
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| 31. Ronde | 09.02.2022 | Queens Park Rangers | - | Middlesbrough FC | 2:2 | ||||
| 32. Ronde | 12.02.2022 | Middlesbrough FC | - | Derby County | 4:1 | ||||
| 33. Ronde | 19.02.2022 | Bristol City | - | Middlesbrough FC | 2:1 | ||||
| 34. Ronde | 22.02.2022 | Middlesbrough FC | - | West Bromwich Albion | 2:1 | ||||
| 35. Ronde | 26.02.2022 | Barnsley FC | - | Middlesbrough FC | 3:2 | ||||
| 36. Ronde | 05.03.2022 | Middlesbrough FC | - | Luton Town | 2:1 | ||||
| 37. Ronde | 12.03.2022 | Millwall FC | - | Middlesbrough FC | 0:0 | ||||
| 38. Ronde | 15.03.2022 | Birmingham City | - | Middlesbrough FC | 0:2 | ||||
| 30. Ronde | 06.04.2022 | Middlesbrough FC | - | Fulham FC | 0:1 |
Wales