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| 19.09.2010 | 11:00 | SpVgg Erkenschwick | - | SG Wattenscheid 09 | 1:1 (0:1) | |
| 11:00 | Bor. Mönchengladbach | - | MSV Duisburg | 1:2 (0:1) | ||
| 11:00 | Wuppertaler SV | - | FC Schalke 04 | 0:4 (0:1) | ||
| 11:00 | Borussia Dortmund | - | Rot Weiss Ahlen | 2:1 (1:1) | ||
| 11:00 | Bayer Leverkusen | - | 1. FC Köln | 7:0 (3:0) | ||
| 11:00 | VfL Bochum | - | Bonner SC | 2:3 (1:1) | ||
| 15:00 | Arminia Bielefeld | - | Fortuna Düsseldorf | 4:1 (3:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Bayer Leverkusen | 5 | 5 | 0 | 0 | 19:3 | 16 | 15 |
| 2 |
|
MSV Duisburg | 5 | 5 | 0 | 0 | 17:6 | 11 | 15 |
| 3 |
|
FC Schalke 04 | 5 | 4 | 1 | 0 | 16:4 | 12 | 13 |
| 4 |
|
Arminia Bielefeld | 5 | 2 | 2 | 1 | 10:6 | 4 | 8 |
| 5 |
|
Bonner SC | 5 | 2 | 2 | 1 | 7:6 | 1 | 8 |
|
Bor. Mönchengladbach | 5 | 2 | 2 | 1 | 7:6 | 1 | 8 | |
| 7 |
|
Rot Weiss Ahlen | 5 | 2 | 1 | 2 | 9:6 | 3 | 7 |
| 8 |
|
Borussia Dortmund | 5 | 2 | 0 | 3 | 8:11 | -3 | 6 |
| 9 |
|
Wuppertaler SV | 5 | 1 | 2 | 2 | 5:8 | -3 | 5 |
| 10 |
|
VfL Bochum | 5 | 1 | 1 | 3 | 3:7 | -4 | 4 |
| 11 |
|
1. FC Köln | 5 | 1 | 0 | 4 | 6:14 | -8 | 3 |
| 12 |
|
Fortuna Düsseldorf | 5 | 0 | 2 | 3 | 3:9 | -6 | 2 |
| 13 |
|
SpVgg Erkenschwick | 5 | 0 | 2 | 3 | 2:13 | -11 | 2 |
| 14 |
|
SG Wattenscheid 09 | 5 | 0 | 1 | 4 | 7:20 | -13 | 1 |
| Play-offs | |
| Degradatie |
