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| 04.03.2022 | 19:15 | Bayer Leverkusen | - | Werder Bremen | 1:1 (0:1) | |
| 05.03.2022 | 13:00 | Eintracht Frankfurt | - | 1899 Hoffenheim | 3:2 (0:1) | |
| 06.03.2022 | 13:00 | VfL Wolfsburg | - | SC Freiburg | 4:1 (1:0) | |
| 13:00 | FC Carl Zeiss Jena | - | SC Sand | 1:4 (0:2) | ||
| 16:00 | SGS Essen | - | Turbine Potsdam | 0:5 (0:4) | ||
| 16:00 | Bayern München | - | 1. FC Köln | 6:0 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VfL Wolfsburg | 15 | 12 | 2 | 1 | 42:11 | 31 | 38 |
| 2 |
|
Bayern München | 15 | 12 | 1 | 2 | 54:8 | 46 | 37 |
| 3 |
|
1899 Hoffenheim | 15 | 9 | 4 | 2 | 40:20 | 20 | 31 |
| 4 |
|
Eintracht Frankfurt | 15 | 10 | 1 | 4 | 33:17 | 16 | 31 |
| 5 |
|
Turbine Potsdam | 15 | 9 | 3 | 3 | 41:21 | 20 | 30 |
| 6 |
|
Bayer Leverkusen | 15 | 6 | 3 | 6 | 25:29 | -4 | 21 |
| 7 |
|
SC Freiburg | 15 | 5 | 2 | 8 | 20:27 | -7 | 17 |
| 8 |
|
1. FC Köln | 15 | 4 | 4 | 7 | 16:34 | -18 | 16 |
| 9 |
|
SGS Essen | 15 | 3 | 3 | 9 | 18:27 | -9 | 12 |
| 10 |
|
Werder Bremen | 15 | 3 | 3 | 9 | 7:35 | -28 | 12 |
| 11 |
|
SC Sand | 15 | 1 | 2 | 12 | 8:30 | -22 | 5 |
| 12 |
|
FC Carl Zeiss Jena | 15 | 1 | 2 | 12 | 6:51 | -45 | 5 |
| Champions League | |
| Champions League Kwali. | |
| Degradatie |
