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| 22.04.2022 | 19:15 | FC Carl Zeiss Jena | - | Bayern München | 0:4 (0:0) | |
| 23.04.2022 | 14:00 | 1899 Hoffenheim | - | Turbine Potsdam | 1:2 (1:0) | |
| 24.04.2022 | 13:00 | Eintracht Frankfurt | - | Bayer Leverkusen | 2:1 (0:0) | |
| 16:00 | 1. FC Köln | - | Werder Bremen | 1:1 (1:1) | ||
| 18:00 | SC Freiburg | - | SC Sand | 7:1 (5:0) | ||
| 04.05.2022 | 19:15 | SGS Essen | - | VfL Wolfsburg | 1:5 (1:3) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VfL Wolfsburg | 20 | 17 | 2 | 1 | 65:14 | 51 | 53 |
| 2 |
|
Bayern München | 20 | 16 | 1 | 3 | 70:18 | 52 | 49 |
| 3 |
|
Turbine Potsdam | 20 | 13 | 4 | 3 | 52:22 | 30 | 43 |
| 4 |
|
Eintracht Frankfurt | 20 | 13 | 1 | 6 | 43:26 | 17 | 40 |
| 5 |
|
1899 Hoffenheim | 20 | 11 | 4 | 5 | 52:29 | 23 | 37 |
| 6 |
|
SC Freiburg | 20 | 8 | 4 | 8 | 37:31 | 6 | 28 |
| 7 |
|
Bayer Leverkusen | 20 | 6 | 4 | 10 | 30:40 | -10 | 22 |
| 8 |
|
1. FC Köln | 20 | 5 | 6 | 9 | 22:44 | -22 | 21 |
| 9 |
|
Werder Bremen | 20 | 4 | 6 | 10 | 9:41 | -32 | 18 |
| 10 |
|
SGS Essen | 20 | 3 | 5 | 12 | 20:38 | -18 | 14 |
| 11 |
|
SC Sand | 20 | 2 | 3 | 15 | 12:42 | -30 | 9 |
| 12 |
|
FC Carl Zeiss Jena | 20 | 1 | 2 | 17 | 8:75 | -67 | 5 |
| Champions League | |
| Champions League Kwali. | |
| Degradatie |
