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| 23.02.2022 | 14:30 | Mantova 1911 SSD | - | FeralpiSalò | 2:1 (1:0) | |
| 14:30 | Juventus II | - | Aurora Pro Patria | 1:0 (0:0) | ||
| 14:30 | Seregno | - | Pro Vercelli | 1:2 (1:0) | ||
| 18:00 | Calcio Lecco 1912 | - | Giana Erminio | 1:0 (1:0) | ||
| 18:00 | Calcio Padova | - | FC Legnago Salus | 1:1 (0:1) | ||
| 18:00 | Piacenza Calcio | - | US Triestina | 0:2 (0:0) | ||
| 18:00 | AC Pro Sesto | - | US Pergolettese | 2:1 (2:1) | ||
| 18:00 | UC AlbinoLeffe | - | US Fiorenzuola | 0:0 (0:0) | ||
| 18:00 | Virtus Verona | - | AC Renate | 0:0 (0:0) | ||
| 21:00 | Trento Calcio 1921 | - | FC Südtirol | 0:1 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Südtirol | 22 | 16 | 6 | 0 | 29:6 | 23 | 54 |
| 2 |
|
Calcio Padova | 22 | 13 | 7 | 2 | 36:15 | 21 | 46 |
| 3 |
|
FeralpiSalò | 22 | 12 | 6 | 4 | 39:18 | 21 | 42 |
| 4 |
|
AC Renate | 22 | 12 | 5 | 5 | 38:24 | 14 | 41 |
| 5 |
|
US Triestina | 22 | 10 | 7 | 5 | 25:18 | 7 | 37 |
| 6 |
|
Juventus II | 22 | 9 | 5 | 8 | 22:25 | -3 | 32 |
| 7 |
|
Calcio Lecco 1912 | 22 | 9 | 4 | 9 | 28:25 | 3 | 31 |
| 8 |
|
Pro Vercelli | 22 | 7 | 8 | 7 | 22:26 | -4 | 29 |
| 9 |
|
Mantova 1911 SSD | 22 | 5 | 12 | 5 | 22:20 | 2 | 27 |
| 10 |
|
Virtus Verona | 22 | 5 | 12 | 5 | 21:20 | 1 | 27 |
| 11 |
|
UC AlbinoLeffe | 22 | 6 | 8 | 8 | 22:24 | -2 | 26 |
| 12 |
|
Piacenza Calcio | 22 | 5 | 10 | 7 | 25:28 | -3 | 25 |
| 13 |
|
Trento Calcio 1921 | 22 | 6 | 7 | 9 | 19:22 | -3 | 25 |
| 14 |
|
Seregno | 22 | 6 | 5 | 11 | 24:29 | -5 | 23 |
| 15 |
|
US Fiorenzuola | 22 | 5 | 7 | 10 | 19:28 | -9 | 22 |
| 16 |
|
US Pergolettese | 22 | 6 | 5 | 11 | 24:37 | -13 | 22 |
| 17 |
|
Aurora Pro Patria | 22 | 4 | 10 | 8 | 16:27 | -11 | 22 |
| 18 |
|
AC Pro Sesto | 22 | 3 | 11 | 8 | 15:23 | -8 | 20 |
| 19 |
|
FC Legnago Salus | 22 | 5 | 4 | 13 | 20:40 | -20 | 19 |
| 20 |
|
Giana Erminio | 22 | 2 | 9 | 11 | 12:23 | -11 | 15 |
| Promotie | |
| Play-offs | |
| Promotie en degradatie | |
| Degradatie |
