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| 28.11.2021 | 14:30 | VfL Alfter | - | Viktoria Arnoldsweiler | 2:1 (1:1) | |
| 14:30 | FC Hennef 05 | - | Borussia Freialdenhoven | 4:0 (3:0) | ||
| 15:00 | FC Hürth | - | SpVg Frechen 20 | 0:1 (0:0) | ||
| 15:00 | BC Viktoria Glesch-Paffendorf | - | Spvg Wesseling-Urfeld | 6:0 (2:0) | ||
| 15:00 | 1. FC Düren | - | SV Bergisch Gladbach 09 | 1:0 (0:0) | ||
| 15:00 | FC Pesch 1956 | - | Siegburger SV 04 | 4:3 (4:1) | ||
| 15:00 | SV Deutz 05 | - | SV 1914 Eilendorf | 0:2 (0:1) | ||
| 15:30 | VfL 08 Vichttal | - | SV Breinig | 2:3 (1:2) | ||
| 15:30 | Blau-Weiß Friesdorf | - | Fortuna Köln II | 1:3 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Düren | 16 | 12 | 3 | 1 | 45:11 | 34 | 39 |
| 2 |
|
FC Hennef 05 | 16 | 12 | 3 | 1 | 40:10 | 30 | 39 |
| 3 |
|
SV Bergisch Gladbach 09 | 16 | 10 | 4 | 2 | 42:10 | 32 | 34 |
| 4 |
|
SpVg Frechen 20 | 16 | 10 | 3 | 3 | 33:15 | 18 | 33 |
| 5 |
|
Siegburger SV 04 | 16 | 8 | 5 | 3 | 30:18 | 12 | 29 |
| 6 |
|
Borussia Freialdenhoven | 16 | 9 | 1 | 6 | 28:23 | 5 | 28 |
| 7 |
|
Viktoria Arnoldsweiler | 16 | 8 | 1 | 7 | 28:23 | 5 | 25 |
| 8 |
|
FC Pesch 1956 | 16 | 6 | 6 | 4 | 32:20 | 12 | 24 |
| 9 |
|
VfL 08 Vichttal | 16 | 7 | 3 | 6 | 32:29 | 3 | 24 |
| 10 |
|
VfL Alfter | 16 | 7 | 3 | 6 | 24:30 | -6 | 24 |
| 11 |
|
BC Viktoria Glesch-Paffendorf | 16 | 6 | 4 | 6 | 27:20 | 7 | 22 |
| 12 |
|
Blau-Weiß Friesdorf | 16 | 5 | 5 | 6 | 24:29 | -5 | 20 |
| 13 |
|
FC Hürth | 16 | 6 | 2 | 8 | 23:34 | -11 | 20 |
| 14 |
|
SV 1914 Eilendorf | 16 | 3 | 2 | 11 | 14:36 | -22 | 11 |
| 15 |
|
Fortuna Köln II | 16 | 2 | 4 | 10 | 17:35 | -18 | 10 |
| 16 |
|
Spvg Wesseling-Urfeld | 16 | 3 | 0 | 13 | 16:53 | -37 | 9 |
| 17 |
|
SV Deutz 05 | 16 | 2 | 2 | 12 | 14:39 | -25 | 8 |
| 18 |
|
SV Breinig | 16 | 2 | 1 | 13 | 16:50 | -34 | 7 |
| Play-offs | |
| Degradatie |
