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| 05.11.2021 | 20:00 | MSV 1919 Neuruppin | - | Blau-Weiß 90 Berlin | 0:2 (0:1) | |
| 06.11.2021 | 13:30 | RSV Eintracht 1949 | - | Rostocker FC | 4:2 (3:2) | |
| 13:30 | Torgelower FC Greif | - | MSV Pampow | 2:0 (2:0) | ||
| 14:00 | FC Mecklenburg Schwerin | - | CFC Hertha 06 | 0:0 (0:0) | ||
| 14:00 | SC Staaken | - | Brandenburger SC Süd | 2:0 (0:0) | ||
| 07.11.2021 | 13:00 | SFC Stern 1900 | - | 1. FC Lok Stendal | 2:3 (2:1) | |
| 13:30 | Eintracht Mahlsdorf | - | Hansa Rostock II | 2:2 (1:0) | ||
| 13:30 | Victoria Seelow | - | TSG Neustrelitz | 0:3 (0:1) | ||
| 14:00 | Hertha Zehlendorf | - | Greifswalder FC | 2:1 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | ∅ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Rostocker FC | 12 | 9 | 0 | 3 | 32:10 | 22 | 27 | 2.25 |
| 2 |
|
CFC Hertha 06 | 13 | 8 | 3 | 2 | 23:12 | 11 | 27 | 2.08 |
| 3 |
|
Blau-Weiß 90 Berlin | 12 | 8 | 1 | 3 | 25:15 | 10 | 25 | 2.08 |
| 4 |
|
Greifswalder FC | 12 | 7 | 3 | 2 | 21:13 | 8 | 24 | 2.00 |
| 5 |
|
Hertha Zehlendorf | 13 | 8 | 1 | 4 | 27:15 | 12 | 25 | 1.92 |
| 6 |
|
Torgelower FC Greif | 12 | 6 | 3 | 3 | 33:14 | 19 | 21 | 1.75 |
| 7 |
|
SC Staaken | 13 | 6 | 4 | 3 | 25:14 | 11 | 22 | 1.69 |
| 8 |
|
TSG Neustrelitz | 12 | 5 | 5 | 2 | 16:11 | 5 | 20 | 1.67 |
| 9 |
|
RSV Eintracht 1949 | 12 | 5 | 4 | 3 | 19:18 | 1 | 19 | 1.58 |
| 10 |
|
Hansa Rostock II | 12 | 4 | 3 | 5 | 24:24 | 0 | 15 | 1.25 |
| 11 |
|
Eintracht Mahlsdorf | 12 | 4 | 3 | 5 | 16:16 | 0 | 15 | 1.25 |
| 12 |
|
Ludwigsfelder FC | 12 | 4 | 2 | 6 | 15:19 | -4 | 14 | 1.17 |
| 13 |
|
FC Mecklenburg Schwerin | 13 | 4 | 3 | 6 | 19:22 | -3 | 15 | 1.15 |
| 14 |
|
MSV 1919 Neuruppin | 12 | 3 | 3 | 6 | 15:27 | -12 | 12 | 1.00 |
| 15 |
|
MSV Pampow | 12 | 3 | 3 | 6 | 13:25 | -12 | 12 | 1.00 |
| 16 |
|
1. FC Lok Stendal | 12 | 3 | 2 | 7 | 16:33 | -17 | 11 | 0.92 |
| 17 |
|
Victoria Seelow | 13 | 3 | 1 | 9 | 14:34 | -20 | 10 | 0.77 |
| 18 |
|
Brandenburger SC Süd | 13 | 2 | 3 | 8 | 10:22 | -12 | 9 | 0.69 |
| 19 |
|
SFC Stern 1900 | 12 | 0 | 3 | 9 | 13:32 | -19 | 3 | 0.25 |
| Promotie | |
| Promotie en degradatie | |
| Degradatie |
