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| 04.03.2022 | 19:30 | Hertha Zehlendorf | - | Blau-Weiß 90 Berlin | 6:0 (2:0) | |
| 05.03.2022 | 14:00 | Ludwigsfelder FC | - | MSV 1919 Neuruppin | 4:0 (2:0) | |
| 14:00 | RSV Eintracht 1949 | - | SFC Stern 1900 | 5:0 (2:0) | ||
| 15:30 | FC Mecklenburg Schwerin | - | Hansa Rostock II | 0:3 (0:0) | ||
| 06.03.2022 | 14:00 | Greifswalder FC | - | TSG Neustrelitz | 1:0 (1:0) | |
| 14:00 | Eintracht Mahlsdorf | - | Torgelower FC Greif | 2:1 (1:0) | ||
| 14:00 | SC Staaken | - | 1. FC Lok Stendal | 3:0 (1:0) | ||
| 14:00 | Victoria Seelow | - | MSV Pampow | 2:3 (1:1) | ||
| 27.04.2022 | 18:00 | CFC Hertha 06 | - | Rostocker FC | 2:2 (1:2) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | ∅ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Rostocker FC | 18 | 13 | 1 | 4 | 53:15 | 38 | 40 | 2.22 |
| 2 |
|
Blau-Weiß 90 Berlin | 18 | 12 | 1 | 5 | 41:26 | 15 | 37 | 2.06 |
| 3 |
|
Greifswalder FC | 18 | 11 | 4 | 3 | 31:19 | 12 | 37 | 2.06 |
| 4 |
|
SC Staaken | 18 | 10 | 5 | 3 | 36:17 | 19 | 35 | 1.94 |
| 5 |
|
CFC Hertha 06 | 18 | 10 | 5 | 3 | 31:18 | 13 | 35 | 1.94 |
| 6 |
|
Hertha Zehlendorf | 18 | 11 | 1 | 6 | 39:19 | 20 | 34 | 1.89 |
| 7 |
|
RSV Eintracht 1949 | 18 | 8 | 7 | 3 | 33:22 | 11 | 31 | 1.72 |
| 8 |
|
Torgelower FC Greif | 18 | 8 | 4 | 6 | 42:22 | 20 | 28 | 1.56 |
| 9 |
|
TSG Neustrelitz | 18 | 7 | 6 | 5 | 20:17 | 3 | 27 | 1.50 |
| 10 |
|
Eintracht Mahlsdorf | 18 | 7 | 4 | 7 | 28:26 | 2 | 25 | 1.39 |
| 11 |
|
MSV Pampow | 18 | 7 | 4 | 7 | 28:34 | -6 | 25 | 1.39 |
| 12 |
|
Hansa Rostock II | 18 | 6 | 6 | 6 | 32:30 | 2 | 24 | 1.33 |
| 13 |
|
Ludwigsfelder FC | 18 | 7 | 2 | 9 | 25:32 | -7 | 23 | 1.28 |
| 14 |
|
FC Mecklenburg Schwerin | 18 | 6 | 3 | 9 | 24:34 | -10 | 21 | 1.17 |
| 15 |
|
MSV 1919 Neuruppin | 18 | 3 | 5 | 10 | 18:40 | -22 | 14 | 0.78 |
| 16 |
|
Victoria Seelow | 18 | 3 | 3 | 12 | 20:49 | -29 | 12 | 0.67 |
| 17 |
|
1. FC Lok Stendal | 18 | 3 | 3 | 12 | 20:51 | -31 | 12 | 0.67 |
| 18 |
|
Brandenburger SC Süd | 18 | 2 | 4 | 12 | 12:32 | -20 | 10 | 0.56 |
| 19 |
|
SFC Stern 1900 | 18 | 0 | 6 | 12 | 18:48 | -30 | 6 | 0.33 |
| Promotie | |
| Promotie en degradatie | |
| Degradatie |
