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| 28.01.2001 | SF Oestrich-Iserlohn | - | FC Schalke 04 II | 1:1 | ||
| Preußen Lengerich | - | FCE Rheine | 1:1 | |||
| SC Paderborn 07 | - | TuS Hordel | 5:0 | |||
| TSG Sprockhövel | - | VfB Hüls | 1:2 | |||
| SC Herford | - | Westfalia Herne | 1:1 | |||
| VfB Kirchellen | - | SuS Stadtlohn | 2:2 | |||
| 29.03.2001 | SG Wattenscheid 09 II | - | SpVgg Beckum | 1:0 | ||
| 04.04.2001 | FC Gütersloh 2000 | - | Lüner SV | 2:1 | ||
| VfL Bochum II | - | TSG Dülmen | 3:2 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VfB Hüls | 20 | 14 | 3 | 3 | 63:26 | 37 | 45 |
| 2 |
|
SC Paderborn 07 | 20 | 13 | 4 | 3 | 43:16 | 27 | 43 |
| 3 |
|
VfL Bochum II | 20 | 11 | 6 | 3 | 46:16 | 30 | 39 |
| 4 |
|
SG Wattenscheid 09 II | 20 | 8 | 9 | 3 | 27:14 | 13 | 33 |
| 5 |
|
Westfalia Herne | 20 | 9 | 6 | 5 | 34:22 | 12 | 33 |
| 6 |
|
FCE Rheine | 20 | 10 | 2 | 8 | 41:35 | 6 | 32 |
| 7 |
|
FC Gütersloh 2000 | 20 | 8 | 7 | 5 | 35:27 | 8 | 31 |
| 8 |
|
SF Oestrich-Iserlohn | 20 | 8 | 7 | 5 | 27:30 | -3 | 31 |
| 9 |
|
FC Schalke 04 II | 20 | 8 | 6 | 6 | 42:37 | 5 | 30 |
| 10 |
|
Lüner SV | 20 | 7 | 7 | 6 | 32:29 | 3 | 28 |
| 11 |
|
TSG Dülmen | 20 | 6 | 8 | 6 | 26:30 | -4 | 26 |
| 12 |
|
SV Lippstadt 08 | 19 | 6 | 6 | 7 | 34:29 | 5 | 24 |
| 13 |
|
SuS Stadtlohn | 20 | 5 | 8 | 7 | 27:34 | -7 | 23 |
| 14 |
|
TuS Hordel | 20 | 7 | 1 | 12 | 34:56 | -22 | 22 |
| 15 |
|
TSG Sprockhövel | 20 | 6 | 3 | 11 | 27:42 | -15 | 21 |
| 16 |
|
SC Herford | 20 | 4 | 7 | 9 | 21:26 | -5 | 19 |
| 17 |
|
Preußen Lengerich | 19 | 3 | 7 | 9 | 23:43 | -20 | 16 |
| 18 |
|
SpVgg Beckum | 20 | 3 | 4 | 13 | 17:50 | -33 | 13 |
| 19 |
|
VfB Kirchellen | 20 | 0 | 5 | 15 | 20:57 | -37 | 5 |
