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| 16.04.2001 | SV Lippstadt 08 | - | VfL Bochum II | 0:2 | ||
| SC Paderborn 07 | - | SC Herford | 4:0 | |||
| SG Wattenscheid 09 II | - | FC Gütersloh 2000 | 5:1 | |||
| TuS Hordel | - | SpVgg Beckum | 4:1 | |||
| FCE Rheine | - | Lüner SV | 0:0 | |||
| FC Schalke 04 II | - | Westfalia Herne | 3:2 | |||
| SF Oestrich-Iserlohn | - | TSG Dülmen | 3:1 | |||
| TSG Sprockhövel | - | VfB Kirchellen | 5:1 | |||
| 10.05.2001 | Preußen Lengerich | - | SuS Stadtlohn | 1:0 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SC Paderborn 07 | 30 | 22 | 5 | 3 | 70:21 | 49 | 71 |
| 2 |
|
VfL Bochum II | 30 | 19 | 7 | 4 | 72:31 | 41 | 64 |
| 3 |
|
VfB Hüls | 30 | 19 | 5 | 6 | 77:35 | 42 | 62 |
| 4 |
|
FC Schalke 04 II | 31 | 15 | 8 | 8 | 70:55 | 15 | 53 |
| 5 |
|
FC Gütersloh 2000 | 30 | 14 | 8 | 8 | 54:38 | 16 | 50 |
| 6 |
|
Westfalia Herne | 30 | 14 | 6 | 10 | 57:35 | 22 | 48 |
| 7 |
|
SG Wattenscheid 09 II | 30 | 12 | 12 | 6 | 45:33 | 12 | 48 |
| 8 |
|
Lüner SV | 30 | 13 | 9 | 8 | 51:42 | 9 | 48 |
| 9 |
|
FCE Rheine | 31 | 13 | 6 | 12 | 56:47 | 9 | 45 |
| 10 |
|
SF Oestrich-Iserlohn | 31 | 12 | 7 | 12 | 46:56 | -10 | 43 |
| 11 |
|
TSG Dülmen | 30 | 10 | 9 | 11 | 37:43 | -6 | 39 |
| 12 |
|
SV Lippstadt 08 | 30 | 9 | 9 | 12 | 49:49 | 0 | 36 |
| 13 |
|
TuS Hordel | 31 | 11 | 3 | 17 | 51:79 | -28 | 36 |
| 14 |
|
SuS Stadtlohn | 30 | 8 | 11 | 11 | 43:47 | -4 | 35 |
| 15 |
|
Preußen Lengerich | 30 | 8 | 8 | 14 | 56:69 | -13 | 32 |
| 16 |
|
TSG Sprockhövel | 30 | 8 | 8 | 14 | 42:62 | -20 | 32 |
| 17 |
|
SC Herford | 30 | 6 | 10 | 14 | 30:49 | -19 | 28 |
| 18 |
|
SpVgg Beckum | 31 | 3 | 6 | 22 | 24:81 | -57 | 15 |
| 19 |
|
VfB Kirchellen | 31 | 1 | 5 | 25 | 30:88 | -58 | 8 |
