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| 23.04.2006 | 15:00 | VfB Hüls | - | Sportfreunde Siegen II | 1:0 | |
| 15:00 | FC Schalke 04 II | - | Arminia Bielefeld II | 4:0 | ||
| 15:00 | Westfalia Herne | - | VfL Bochum II | 2:0 | ||
| 15:00 | SV Schermbeck 1912 | - | SpVgg Erkenschwick | 0:1 | ||
| 15:00 | VfB Fichte Bielefeld | - | Borussia Dortmund II | 1:3 | ||
| 15:00 | LR Ahlen II | - | SV Lippstadt 08 | 1:3 | ||
| 15:00 | SC Verl | - | SV Emsdetten 05 | 2:2 | ||
| 15:00 | Delbrücker SC | - | Sportfreunde Lotte | 2:2 | ||
| 15:00 | FCE Rheine | - | FC Gütersloh 2000 | 2:1 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Borussia Dortmund II | 28 | 20 | 5 | 3 | 66:23 | 43 | 65 |
| 2 |
|
SC Verl | 28 | 18 | 6 | 4 | 66:35 | 31 | 60 |
| 3 |
|
FC Schalke 04 II | 28 | 14 | 7 | 7 | 52:35 | 17 | 49 |
| 4 |
|
Sportfreunde Lotte | 28 | 12 | 11 | 5 | 42:33 | 9 | 47 |
| 5 |
|
FC Gütersloh 2000 | 28 | 12 | 8 | 8 | 59:37 | 22 | 44 |
| 6 |
|
VfL Bochum II | 28 | 13 | 4 | 11 | 51:44 | 7 | 43 |
| 7 |
|
Westfalia Herne | 28 | 12 | 7 | 9 | 43:40 | 3 | 43 |
| 8 |
|
VfB Hüls | 28 | 10 | 7 | 11 | 39:41 | -2 | 37 |
| 9 |
|
FCE Rheine | 28 | 10 | 6 | 12 | 42:51 | -9 | 36 |
| 10 |
|
Delbrücker SC | 28 | 8 | 9 | 11 | 29:39 | -10 | 33 |
| 11 |
|
Arminia Bielefeld II | 28 | 7 | 11 | 10 | 28:31 | -3 | 32 |
| 12 |
|
SV Lippstadt 08 | 28 | 9 | 5 | 14 | 35:57 | -22 | 32 |
| 13 |
|
LR Ahlen II | 28 | 7 | 9 | 12 | 28:36 | -8 | 30 |
| 14 |
|
SV Schermbeck 1912 | 28 | 8 | 5 | 15 | 38:39 | -1 | 29 |
| 15 |
|
SpVgg Erkenschwick | 28 | 7 | 8 | 13 | 25:37 | -12 | 29 |
| 16 |
|
SV Emsdetten 05 | 28 | 7 | 8 | 13 | 30:50 | -20 | 29 |
| 17 |
|
Sportfreunde Siegen II | 28 | 7 | 7 | 14 | 32:53 | -21 | 28 |
| 18 |
|
VfB Fichte Bielefeld | 28 | 6 | 7 | 15 | 25:49 | -24 | 25 |
