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| 20.05.2006 | 15:00 | Westfalia Herne | - | SV Emsdetten 05 | 2:3 | |
| 21.05.2006 | 15:00 | Arminia Bielefeld II | - | Sportfreunde Siegen II | 1:0 | |
| 15:00 | LR Ahlen II | - | VfB Fichte Bielefeld | 2:0 | ||
| 15:00 | SC Verl | - | SV Schermbeck 1912 | 1:1 | ||
| 15:00 | Delbrücker SC | - | SpVgg Erkenschwick | 0:2 | ||
| 15:00 | FCE Rheine | - | Borussia Dortmund II | 0:5 | ||
| 15:00 | FC Schalke 04 II | - | SV Lippstadt 08 | 4:0 | ||
| 15:00 | VfB Hüls | - | Sportfreunde Lotte | 3:0 | ||
| 15:00 | VfL Bochum II | - | FC Gütersloh 2000 | 1:0 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Borussia Dortmund II | 32 | 23 | 6 | 3 | 76:24 | 52 | 75 |
| 2 |
|
SC Verl | 32 | 20 | 7 | 5 | 72:41 | 31 | 67 |
| 3 |
|
FC Schalke 04 II | 32 | 16 | 7 | 9 | 62:41 | 21 | 55 |
| 4 |
|
FC Gütersloh 2000 | 32 | 15 | 8 | 9 | 66:39 | 27 | 53 |
| 5 |
|
Sportfreunde Lotte | 32 | 14 | 11 | 7 | 46:39 | 7 | 53 |
| 6 |
|
VfL Bochum II | 32 | 15 | 5 | 12 | 58:48 | 10 | 50 |
| 7 |
|
VfB Hüls | 32 | 13 | 7 | 12 | 48:48 | 0 | 46 |
| 8 |
|
Westfalia Herne | 32 | 12 | 7 | 13 | 46:49 | -3 | 43 |
| 9 |
|
Arminia Bielefeld II | 32 | 9 | 12 | 11 | 33:35 | -2 | 39 |
| 10 |
|
LR Ahlen II | 32 | 10 | 9 | 13 | 34:38 | -4 | 39 |
| 11 |
|
SV Emsdetten 05 | 32 | 10 | 9 | 13 | 40:56 | -16 | 39 |
| 12 |
|
Delbrücker SC | 32 | 9 | 11 | 12 | 32:43 | -11 | 38 |
| 13 |
|
FCE Rheine | 32 | 10 | 6 | 16 | 42:62 | -20 | 36 |
| 14 |
|
SpVgg Erkenschwick | 32 | 9 | 8 | 15 | 30:43 | -13 | 35 |
| 15 |
|
SV Lippstadt 08 | 32 | 10 | 5 | 17 | 40:65 | -25 | 35 |
| 16 |
|
SV Schermbeck 1912 | 32 | 9 | 6 | 17 | 41:42 | -1 | 33 |
| 17 |
|
Sportfreunde Siegen II | 32 | 8 | 7 | 17 | 36:60 | -24 | 31 |
| 18 |
|
VfB Fichte Bielefeld | 32 | 7 | 7 | 18 | 28:57 | -29 | 28 |
