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| 05.11.2022 | 14:00 | SV 19 Straelen | - | 1. FC Köln II | 0:0 (0:0) | |
| 14:00 | Bor. Mönchengladbach II | - | SV Lippstadt 08 | 4:2 (2:0) | ||
| 14:00 | Alemannia Aachen | - | SV Rödinghausen | 3:1 (1:1) | ||
| 14:00 | 1. FC Bocholt | - | FC Schalke 04 II | 2:8 (0:6) | ||
| 14:00 | SC Wiedenbrück | - | 1. FC Kaan-Marienborn | 1:2 (1:2) | ||
| 14:00 | SG Wattenscheid 09 | - | Rot-Weiß Oberhausen | 1:1 (0:0) | ||
| 14:00 | Rot Weiss Ahlen | - | 1. FC Düren | 1:2 (0:0) | ||
| 14:00 | Wuppertaler SV | - | Fortuna Düsseldorf II | 4:1 (2:1) | ||
| 06.11.2022 | 14:00 | Fortuna Köln | - | Preußen Münster | 1:3 (0:1) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Preußen Münster | 15 | 11 | 2 | 2 | 40:15 | 25 | 35 |
| 2 |
|
Alemannia Aachen | 15 | 8 | 3 | 4 | 26:20 | 6 | 27 |
| 3 |
|
SV Rödinghausen | 15 | 8 | 2 | 5 | 29:14 | 15 | 26 |
| 4 |
|
Bor. Mönchengladbach II | 15 | 7 | 5 | 3 | 28:19 | 9 | 26 |
| 5 |
|
Wuppertaler SV | 15 | 7 | 4 | 4 | 28:19 | 9 | 25 |
| 6 |
|
FC Schalke 04 II | 15 | 7 | 3 | 5 | 34:23 | 11 | 24 |
| 7 |
|
1. FC Kaan-Marienborn | 15 | 7 | 3 | 5 | 22:24 | -2 | 24 |
| 8 |
|
Fortuna Köln | 15 | 7 | 3 | 5 | 17:19 | -2 | 24 |
| 9 |
|
Rot-Weiß Oberhausen | 15 | 6 | 4 | 5 | 28:28 | 0 | 22 |
| 10 |
|
SV Lippstadt 08 | 15 | 7 | 1 | 7 | 26:29 | -3 | 22 |
| 11 |
|
Rot Weiss Ahlen | 15 | 5 | 4 | 6 | 28:26 | 2 | 19 |
| 12 |
|
Fortuna Düsseldorf II | 15 | 6 | 1 | 8 | 24:33 | -9 | 19 |
| 13 |
|
1. FC Düren | 15 | 6 | 1 | 8 | 18:28 | -10 | 19 |
| 14 |
|
1. FC Bocholt | 15 | 5 | 3 | 7 | 26:34 | -8 | 18 |
| 15 |
|
SC Wiedenbrück | 15 | 4 | 5 | 6 | 22:19 | 3 | 17 |
| 16 |
|
1. FC Köln II | 15 | 5 | 2 | 8 | 23:32 | -9 | 17 |
| 17 |
|
SG Wattenscheid 09 | 15 | 2 | 3 | 10 | 16:39 | -23 | 9 |
| 18 |
|
SV 19 Straelen | 15 | 2 | 1 | 12 | 10:24 | -14 | 7 |
| Promotie | |
| Degradatie | |
| Degradatie |
