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| 02.10.2021 | 11:00 | SpVgg Unterhaching | - | FC-Astoria Walldorf | 4:3 (1:1) | |
| 11:00 | FC Augsburg | - | 1. FC Saarbrücken | 0:1 (0:0) | ||
| 11:00 | Bayern München | - | VfB Stuttgart | 1:4 (1:0) | ||
| 11:00 | SSV Ulm 1846 | - | Eintracht Frankfurt | 1:2 (0:0) | ||
| 12:00 | Kickers Offenbach | - | Hessen Kassel | 3:0 (1:0) | ||
| 12:30 | 1. FC Kaiserslautern | - | Karlsruher SC | 4:3 (2:1) | ||
| 13:00 | SV Darmstadt 98 | - | SpVgg Greuther Fürth | 0:0 (0:0) | ||
| 13:30 | Stuttgarter Kickers | - | 1. FSV Mainz 05 | 2:1 (1:1) | ||
| 14:00 | 1. FC Heidenheim 1846 | - | 1. FC Nürnberg | 1:2 (0:1) | ||
| 29.01.2022 | 14:00 | SC Freiburg | - | 1899 Hoffenheim | 3:3 (2:2) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VfB Stuttgart | 6 | 5 | 0 | 1 | 20:6 | 14 | 15 |
| 2 |
|
1. FC Nürnberg | 6 | 5 | 0 | 1 | 15:9 | 6 | 15 |
| 3 |
|
1899 Hoffenheim | 6 | 4 | 1 | 1 | 27:13 | 14 | 13 |
| 4 |
|
Eintracht Frankfurt | 6 | 4 | 1 | 1 | 19:6 | 13 | 13 |
| 5 |
|
FC Augsburg | 5 | 4 | 0 | 1 | 9:5 | 4 | 12 |
| 6 |
|
SpVgg Unterhaching | 6 | 3 | 2 | 1 | 10:7 | 3 | 11 |
| 7 |
|
1. FC Heidenheim 1846 | 6 | 3 | 1 | 2 | 12:8 | 4 | 10 |
| 8 |
|
SV Darmstadt 98 | 6 | 3 | 1 | 2 | 7:13 | -6 | 10 |
| 9 |
|
1. FSV Mainz 05 | 6 | 3 | 0 | 3 | 21:12 | 9 | 9 |
| 10 |
|
FC Ingolstadt 04 | 5 | 2 | 1 | 2 | 11:10 | 1 | 7 |
| 11 |
|
SC Freiburg | 6 | 2 | 1 | 3 | 13:17 | -4 | 7 |
| 12 |
|
Bayern München | 5 | 2 | 0 | 3 | 11:9 | 2 | 6 |
| 13 |
|
Karlsruher SC | 5 | 1 | 3 | 1 | 8:7 | 1 | 6 |
| 14 |
|
SpVgg Greuther Fürth | 6 | 1 | 3 | 2 | 6:8 | -2 | 6 |
| 15 |
|
SSV Ulm 1846 | 5 | 2 | 0 | 3 | 5:7 | -2 | 6 |
| 16 |
|
Kickers Offenbach | 6 | 2 | 0 | 4 | 8:16 | -8 | 6 |
| 17 |
|
1. FC Kaiserslautern | 6 | 2 | 0 | 4 | 13:23 | -10 | 6 |
| 18 |
|
Stuttgarter Kickers | 6 | 2 | 0 | 4 | 10:20 | -10 | 6 |
| 19 |
|
1. FC Saarbrücken | 6 | 1 | 0 | 5 | 5:15 | -10 | 3 |
| 20 |
|
Hessen Kassel | 6 | 1 | 0 | 5 | 4:14 | -10 | 3 |
| 21 |
|
FC-Astoria Walldorf | 5 | 0 | 2 | 3 | 5:14 | -9 | 2 |
| Play-offs | |
| Degradatie |
