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| 16.01.2021 | 14:00 | Eintracht Stadtallendorf | - | TSG Balingen | 0:3 (0:1) | |
| 14:00 | FC Gießen | - | Bayern Alzenau | 1:0 (1:0) | ||
| 14:00 | SSV Ulm 1846 | - | FK Pirmasens | 4:0 (0:0) | ||
| 14:00 | FSV Frankfurt | - | 1. FSV Mainz 05 II | 2:1 (1:1) | ||
| 14:00 | Hessen Kassel | - | 1899 Hoffenheim II | 2:2 (0:1) | ||
| 14:00 | Rot-Weiß Koblenz | - | Bahlinger SC | 1:0 (1:0) | ||
| 14:00 | SV 07 Elversberg | - | SG Sonnenhof Großaspach | 4:0 (2:0) | ||
| 14:00 | TSV Schott Mainz | - | TSV Steinbach Haiger | 1:3 (1:2) | ||
| 14:00 | VfB Stuttgart II | - | SC Freiburg II | 1:2 (1:0) | ||
| 14:00 | FC-Astoria Walldorf | - | VfR Aalen | 1:0 (1:0) | ||
| 02.03.2021 | 17:00 | FC 08 Homburg | - | Kickers Offenbach | 1:2 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SC Freiburg II | 15 | 10 | 2 | 3 | 39:17 | 22 | 32 |
| 2 |
|
Kickers Offenbach | 15 | 9 | 4 | 2 | 31:10 | 21 | 31 |
| 3 |
|
TSV Steinbach Haiger | 15 | 9 | 2 | 4 | 33:16 | 17 | 29 |
| 4 |
|
FSV Frankfurt | 15 | 9 | 2 | 4 | 24:17 | 7 | 29 |
| 5 |
|
SV 07 Elversberg | 15 | 8 | 4 | 3 | 34:17 | 17 | 28 |
| 6 |
|
SSV Ulm 1846 | 15 | 8 | 4 | 3 | 28:11 | 17 | 28 |
| 7 |
|
TSG Balingen | 15 | 8 | 4 | 3 | 26:16 | 10 | 28 |
| 8 |
|
FC 08 Homburg | 15 | 7 | 3 | 5 | 30:20 | 10 | 24 |
| 9 |
|
VfB Stuttgart II | 15 | 6 | 3 | 6 | 25:20 | 5 | 21 |
| 10 |
|
Bahlinger SC | 15 | 6 | 3 | 6 | 27:34 | -7 | 21 |
| 11 |
|
1. FSV Mainz 05 II | 15 | 5 | 4 | 6 | 18:25 | -7 | 19 |
| 12 |
|
FK Pirmasens | 15 | 5 | 4 | 6 | 12:23 | -11 | 19 |
| 13 |
|
1899 Hoffenheim II | 15 | 5 | 3 | 7 | 20:25 | -5 | 18 |
| 14 |
|
SG Sonnenhof Großaspach | 15 | 5 | 3 | 7 | 19:28 | -9 | 18 |
| 15 |
|
VfR Aalen | 15 | 5 | 3 | 7 | 17:26 | -9 | 18 |
| 16 |
|
Bayern Alzenau | 15 | 5 | 2 | 8 | 17:26 | -9 | 17 |
| 17 |
|
TSV Schott Mainz | 15 | 5 | 1 | 9 | 25:38 | -13 | 16 |
| 18 |
|
Hessen Kassel | 15 | 3 | 6 | 6 | 22:30 | -8 | 15 |
| 19 |
|
FC-Astoria Walldorf | 15 | 4 | 3 | 8 | 20:28 | -8 | 15 |
| 20 |
|
Rot-Weiß Koblenz | 15 | 4 | 3 | 8 | 13:24 | -11 | 15 |
| 21 |
|
FC Gießen | 15 | 4 | 2 | 9 | 14:22 | -8 | 14 |
| 22 |
|
Eintracht Stadtallendorf | 15 | 1 | 3 | 11 | 14:35 | -21 | 6 |
| Promotie | |
| Degradatie |
