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| 21.10.2022 | 19:00 | Kickers Offenbach | - | SSV Ulm 1846 | 3:1 (1:0) | |
| 19:00 | FC 08 Homburg | - | 1. FSV Mainz 05 II | 0:3 (0:1) | ||
| 19:00 | TSG Balingen | - | Bahlinger SC | 4:0 (3:0) | ||
| 22.10.2022 | 14:00 | SG Barockstadt Fulda-Lehnerz | - | Rot-Weiß Koblenz | 1:1 (1:1) | |
| 14:00 | FSV Frankfurt | - | 1899 Hoffenheim II | 1:2 (1:2) | ||
| 14:00 | FC-Astoria Walldorf | - | VfB Stuttgart II | 1:0 (0:0) | ||
| 14:00 | Hessen Kassel | - | TSV Steinbach Haiger | 2:0 (1:0) | ||
| 14:00 | VfR Aalen | - | Eintracht Trier | 3:1 (1:0) | ||
| 14:00 | SGV Freiberg | - | Wormatia Worms | 2:2 (1:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SSV Ulm 1846 | 13 | 9 | 3 | 1 | 26:9 | 17 | 30 |
| 2 |
|
TSV Steinbach Haiger | 13 | 8 | 1 | 4 | 28:15 | 13 | 25 |
| 3 |
|
Kickers Offenbach | 13 | 7 | 3 | 3 | 25:13 | 12 | 24 |
| 4 |
|
1899 Hoffenheim II | 13 | 7 | 2 | 4 | 30:24 | 6 | 23 |
| 5 |
|
FC 08 Homburg | 13 | 7 | 1 | 5 | 27:19 | 8 | 22 |
| 6 |
|
1. FSV Mainz 05 II | 13 | 7 | 1 | 5 | 24:18 | 6 | 22 |
| 7 |
|
SG Barockstadt Fulda-Lehnerz | 13 | 5 | 6 | 2 | 22:15 | 7 | 21 |
| 8 |
|
Bahlinger SC | 13 | 7 | 0 | 6 | 16:21 | -5 | 21 |
| 9 |
|
TSG Balingen | 13 | 5 | 5 | 3 | 20:16 | 4 | 20 |
| 10 |
|
VfB Stuttgart II | 13 | 4 | 5 | 4 | 18:18 | 0 | 17 |
| 11 |
|
FSV Frankfurt | 13 | 5 | 2 | 6 | 18:22 | -4 | 17 |
| 12 |
|
FC-Astoria Walldorf | 13 | 4 | 3 | 6 | 21:29 | -8 | 15 |
| 13 |
|
SGV Freiberg | 13 | 3 | 5 | 5 | 16:20 | -4 | 14 |
| 14 |
|
Wormatia Worms | 13 | 4 | 2 | 7 | 13:20 | -7 | 14 |
| 15 |
|
Eintracht Trier | 13 | 3 | 3 | 7 | 14:24 | -10 | 12 |
| 16 |
|
Hessen Kassel | 13 | 2 | 3 | 8 | 10:22 | -12 | 9 |
| 17 |
|
Rot-Weiß Koblenz | 13 | 1 | 3 | 9 | 10:28 | -18 | 6 |
| 18 |
|
VfR Aalen | 13 | 4 | 2 | 7 | 18:23 | -5 | 5 |
| Promotie | |
| Degradatie |
