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| 21.10.2022 | 19:00 | SC Wiedenbrück | - | SV Rödinghausen | 1:1 (1:1) | |
| 19:30 | Alemannia Aachen | - | 1. FC Köln II | 3:1 (2:1) | ||
| 22.10.2022 | 14:00 | Preußen Münster | - | 1. FC Düren | 2:0 (0:0) | |
| 14:00 | 1. FC Bocholt | - | SV Lippstadt 08 | 1:3 (1:0) | ||
| 14:00 | Rot Weiss Ahlen | - | 1. FC Kaan-Marienborn | 3:1 (0:0) | ||
| 14:00 | Wuppertaler SV | - | Rot-Weiß Oberhausen | 1:0 (1:0) | ||
| 23.10.2022 | 14:00 | Fortuna Köln | - | Fortuna Düsseldorf II | 1:4 (0:2) | |
| 14:00 | Bor. Mönchengladbach II | - | SV 19 Straelen | 2:1 (1:1) | ||
| 14:00 | SG Wattenscheid 09 | - | FC Schalke 04 II | 2:1 (2:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Preußen Münster | 13 | 9 | 2 | 2 | 31:13 | 18 | 29 |
| 2 |
|
SV Rödinghausen | 13 | 8 | 2 | 3 | 28:10 | 18 | 26 |
| 3 |
|
SV Lippstadt 08 | 13 | 7 | 1 | 5 | 24:24 | 0 | 22 |
| 4 |
|
Alemannia Aachen | 13 | 6 | 3 | 4 | 22:19 | 3 | 21 |
| 5 |
|
Rot-Weiß Oberhausen | 13 | 6 | 3 | 4 | 25:24 | 1 | 21 |
| 6 |
|
Fortuna Köln | 13 | 6 | 3 | 4 | 15:16 | -1 | 21 |
| 7 |
|
FC Schalke 04 II | 13 | 6 | 2 | 5 | 25:20 | 5 | 20 |
| 8 |
|
Bor. Mönchengladbach II | 13 | 5 | 5 | 3 | 22:17 | 5 | 20 |
| 9 |
|
Wuppertaler SV | 13 | 5 | 4 | 4 | 22:18 | 4 | 19 |
| 10 |
|
Fortuna Düsseldorf II | 13 | 6 | 1 | 6 | 22:23 | -1 | 19 |
| 11 |
|
1. FC Kaan-Marienborn | 13 | 5 | 3 | 5 | 18:22 | -4 | 18 |
| 12 |
|
SC Wiedenbrück | 13 | 4 | 4 | 5 | 20:16 | 4 | 16 |
| 13 |
|
Rot Weiss Ahlen | 13 | 4 | 4 | 5 | 24:22 | 2 | 16 |
| 14 |
|
1. FC Köln II | 13 | 5 | 1 | 7 | 23:30 | -7 | 16 |
| 15 |
|
1. FC Düren | 13 | 5 | 1 | 7 | 16:25 | -9 | 16 |
| 16 |
|
1. FC Bocholt | 13 | 4 | 3 | 6 | 23:26 | -3 | 15 |
| 17 |
|
SG Wattenscheid 09 | 13 | 2 | 2 | 9 | 14:36 | -22 | 8 |
| 18 |
|
SV 19 Straelen | 13 | 2 | 0 | 11 | 10:23 | -13 | 6 |
| Promotie | |
| Degradatie | |
| Degradatie |
