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| 15.10.2010 | 20:30 | 1. FC Köln | - | Borussia Dortmund | 1:2 (0:1) | |
| 16.10.2010 | 15:30 | Bayern München | - | Hannover 96 | 3:0 (1:0) | |
| 15:30 | FC Schalke 04 | - | VfB Stuttgart | 2:2 (1:1) | ||
| 15:30 | Werder Bremen | - | SC Freiburg | 2:1 (1:0) | ||
| 15:30 | 1. FSV Mainz 05 | - | Hamburger SV | 0:1 (0:0) | ||
| 15:30 | FC St. Pauli | - | 1. FC Nürnberg | 3:2 (1:0) | ||
| 18:30 | VfL Wolfsburg | - | Bayer Leverkusen | 2:3 (1:0) | ||
| 17.10.2010 | 15:30 | 1. FC Kaiserslautern | - | Eintracht Frankfurt | 0:3 (0:1) | |
| 17:30 | 1899 Hoffenheim | - | Bor. Mönchengladbach | 3:2 (0:1) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Borussia Dortmund | 8 | 7 | 0 | 1 | 20:6 | 14 | 21 |
| 2 |
|
1. FSV Mainz 05 | 8 | 7 | 0 | 1 | 18:8 | 10 | 21 |
| 3 |
|
Bayer Leverkusen | 8 | 4 | 3 | 1 | 18:14 | 4 | 15 |
| 4 |
|
1899 Hoffenheim | 8 | 4 | 2 | 2 | 16:12 | 4 | 14 |
| 5 |
|
Hamburger SV | 8 | 4 | 2 | 2 | 13:11 | 2 | 14 |
| 6 |
|
FC St. Pauli | 8 | 4 | 1 | 3 | 11:10 | 1 | 13 |
| 7 |
|
Hannover 96 | 8 | 4 | 1 | 3 | 11:11 | 0 | 13 |
| 8 |
|
Eintracht Frankfurt | 8 | 4 | 0 | 4 | 14:9 | 5 | 12 |
| 9 |
|
SC Freiburg | 8 | 4 | 0 | 4 | 12:13 | -1 | 12 |
| 10 |
|
Bayern München | 8 | 3 | 2 | 3 | 8:8 | 0 | 11 |
| 11 |
|
Werder Bremen | 8 | 3 | 2 | 3 | 13:17 | -4 | 11 |
| 12 |
|
VfL Wolfsburg | 8 | 3 | 1 | 4 | 14:14 | 0 | 10 |
| 13 |
|
1. FC Nürnberg | 8 | 2 | 3 | 3 | 9:11 | -2 | 9 |
| 14 |
|
1. FC Kaiserslautern | 8 | 2 | 1 | 5 | 9:16 | -7 | 7 |
| 15 |
|
Bor. Mönchengladbach | 8 | 1 | 3 | 4 | 13:23 | -10 | 6 |
| 16 |
|
FC Schalke 04 | 8 | 1 | 2 | 5 | 10:16 | -6 | 5 |
| 17 |
|
1. FC Köln | 8 | 1 | 2 | 5 | 8:15 | -7 | 5 |
| 18 |
|
VfB Stuttgart | 8 | 1 | 1 | 6 | 14:17 | -3 | 4 |
| Champions League | |
| Champions League Kwali. | |
| Europa League | |
| Promotie en degradatie | |
| Degradatie |
