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| 20.11.2015 | 18:30 | Fortuna Düsseldorf | - | MSV Duisburg | 1:1 (0:0) | |
| 18:30 | VfL Bochum | - | 1. FC Union Berlin | 1:1 (1:1) | ||
| 18:30 | SV Sandhausen | - | Karlsruher SC | 3:1 (2:0) | ||
| 21.11.2015 | 13:00 | TSV 1860 München | - | FC St. Pauli | 2:0 (0:0) | |
| 13:00 | Arminia Bielefeld | - | RB Leipzig | 0:1 (0:1) | ||
| 22.11.2015 | 13:30 | SC Freiburg | - | SC Paderborn 07 | 4:1 (3:0) | |
| 13:30 | 1. FC Kaiserslautern | - | FSV Frankfurt | 1:1 (0:1) | ||
| 13:30 | 1. FC Heidenheim 1846 | - | SpVgg Greuther Fürth | 1:2 (0:1) | ||
| 23.11.2015 | 20:15 | 1. FC Nürnberg | - | Eintracht Braunschweig | 2:1 (1:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SC Freiburg | 15 | 8 | 5 | 2 | 34:19 | 15 | 29 |
| 2 |
|
RB Leipzig | 15 | 8 | 5 | 2 | 21:14 | 7 | 29 |
| 3 |
|
FC St. Pauli | 15 | 7 | 5 | 3 | 19:13 | 6 | 26 |
| 4 |
|
SV Sandhausen | 15 | 8 | 4 | 3 | 26:16 | 10 | 25 |
| 5 |
|
SpVgg Greuther Fürth | 15 | 7 | 3 | 5 | 21:24 | -3 | 24 |
| 6 |
|
VfL Bochum | 15 | 6 | 5 | 4 | 23:16 | 7 | 23 |
| 7 |
|
Eintracht Braunschweig | 15 | 6 | 4 | 5 | 23:13 | 10 | 22 |
| 8 |
|
1. FC Nürnberg | 15 | 5 | 6 | 4 | 27:25 | 2 | 21 |
| 9 |
|
1. FC Heidenheim 1846 | 15 | 5 | 5 | 5 | 16:13 | 3 | 20 |
| 10 |
|
1. FC Kaiserslautern | 15 | 5 | 4 | 6 | 16:19 | -3 | 19 |
| 11 |
|
Karlsruher SC | 15 | 5 | 4 | 6 | 15:21 | -6 | 19 |
| 12 |
|
FSV Frankfurt | 15 | 5 | 4 | 6 | 14:20 | -6 | 19 |
| 13 |
|
1. FC Union Berlin | 15 | 3 | 7 | 5 | 26:26 | 0 | 16 |
| 14 |
|
Arminia Bielefeld | 15 | 2 | 10 | 3 | 12:13 | -1 | 16 |
| 15 |
|
SC Paderborn 07 | 15 | 4 | 3 | 8 | 12:23 | -11 | 15 |
| 16 |
|
TSV 1860 München | 15 | 2 | 7 | 6 | 10:15 | -5 | 13 |
| 17 |
|
Fortuna Düsseldorf | 15 | 3 | 4 | 8 | 12:20 | -8 | 13 |
| 18 |
|
MSV Duisburg | 15 | 1 | 5 | 9 | 10:27 | -17 | 8 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
