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| 11.12.2015 | 18:30 | VfL Bochum | - | SC Paderborn 07 | 4:0 (3:0) | |
| 18:30 | SV Sandhausen | - | Eintracht Braunschweig | 0:2 (0:0) | ||
| 18:30 | TSV 1860 München | - | 1. FC Heidenheim 1846 | 1:3 (1:1) | ||
| 12.12.2015 | 13:00 | Fortuna Düsseldorf | - | 1. FC Union Berlin | 0:3 (0:1) | |
| 13:00 | Karlsruher SC | - | SpVgg Greuther Fürth | 1:0 (0:0) | ||
| 13.12.2015 | 13:30 | 1. FC Kaiserslautern | - | MSV Duisburg | 2:0 (0:0) | |
| 13:30 | 1. FC Nürnberg | - | SC Freiburg | 2:1 (1:0) | ||
| 13:30 | RB Leipzig | - | FSV Frankfurt | 3:1 (0:0) | ||
| 14.12.2015 | 20:15 | Arminia Bielefeld | - | FC St. Pauli | 0:0 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RB Leipzig | 18 | 11 | 5 | 2 | 29:17 | 12 | 38 |
| 2 |
|
SC Freiburg | 18 | 10 | 5 | 3 | 40:22 | 18 | 35 |
| 3 |
|
1. FC Nürnberg | 18 | 8 | 6 | 4 | 35:27 | 8 | 30 |
| 4 |
|
FC St. Pauli | 18 | 8 | 6 | 4 | 21:18 | 3 | 30 |
| 5 |
|
Eintracht Braunschweig | 18 | 8 | 4 | 6 | 26:14 | 12 | 28 |
| 6 |
|
VfL Bochum | 18 | 7 | 6 | 5 | 28:18 | 10 | 27 |
| 7 |
|
SV Sandhausen | 18 | 8 | 5 | 5 | 27:22 | 5 | 26 |
| 8 |
|
1. FC Kaiserslautern | 18 | 7 | 4 | 7 | 23:23 | 0 | 25 |
| 9 |
|
SpVgg Greuther Fürth | 18 | 7 | 4 | 7 | 24:30 | -6 | 25 |
| 10 |
|
1. FC Heidenheim 1846 | 18 | 6 | 6 | 6 | 21:17 | 4 | 24 |
| 11 |
|
Karlsruher SC | 18 | 6 | 4 | 8 | 17:24 | -7 | 22 |
| 12 |
|
FSV Frankfurt | 18 | 6 | 4 | 8 | 17:25 | -8 | 22 |
| 13 |
|
Arminia Bielefeld | 18 | 3 | 12 | 3 | 15:15 | 0 | 21 |
| 14 |
|
1. FC Union Berlin | 18 | 4 | 8 | 6 | 30:30 | 0 | 20 |
| 15 |
|
Fortuna Düsseldorf | 18 | 5 | 4 | 9 | 15:24 | -9 | 19 |
| 16 |
|
SC Paderborn 07 | 18 | 4 | 4 | 10 | 17:33 | -16 | 16 |
| 17 |
|
TSV 1860 München | 18 | 2 | 8 | 8 | 15:23 | -8 | 14 |
| 18 |
|
MSV Duisburg | 18 | 2 | 5 | 11 | 15:33 | -18 | 11 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
