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| 08.03.2019 | 18:30 | 1. FC Union Berlin | - | FC Ingolstadt 04 | 2:0 (1:0) | |
| 18:30 | VfL Bochum | - | 1. FC Heidenheim 1846 | 1:0 (0:0) | ||
| 09.03.2019 | 13:00 | SV Darmstadt 98 | - | Holstein Kiel | 3:2 (2:1) | |
| 13:00 | 1. FC Köln | - | Arminia Bielefeld | 5:1 (2:0) | ||
| 13:00 | Jahn Regensburg | - | MSV Duisburg | 1:1 (1:0) | ||
| 13:00 | Erzgebirge Aue | - | SC Paderborn 07 | 2:1 (1:0) | ||
| 10.03.2019 | 13:30 | FC St. Pauli | - | Hamburger SV | 0:4 (0:1) | |
| 13:30 | 1. FC Magdeburg | - | SV Sandhausen | 0:1 (0:0) | ||
| 04.04.2019 | 19:00 | SpVgg Greuther Fürth | - | Dynamo Dresden | 0:0 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Köln | 25 | 16 | 3 | 6 | 64:31 | 33 | 51 |
| 2 |
|
Hamburger SV | 25 | 15 | 5 | 5 | 36:26 | 10 | 50 |
| 3 |
|
1. FC Union Berlin | 25 | 12 | 11 | 2 | 41:21 | 20 | 47 |
| 4 |
|
FC St. Pauli | 25 | 13 | 4 | 8 | 38:36 | 2 | 43 |
| 5 |
|
Holstein Kiel | 25 | 10 | 9 | 6 | 46:36 | 10 | 39 |
| 6 |
|
1. FC Heidenheim 1846 | 25 | 10 | 9 | 6 | 38:31 | 7 | 39 |
| 7 |
|
SC Paderborn 07 | 25 | 10 | 8 | 7 | 55:39 | 16 | 38 |
| 8 |
|
Jahn Regensburg | 25 | 9 | 10 | 6 | 38:36 | 2 | 37 |
| 9 |
|
VfL Bochum | 25 | 9 | 7 | 9 | 36:36 | 0 | 34 |
| 10 |
|
Erzgebirge Aue | 25 | 9 | 5 | 11 | 32:30 | 2 | 32 |
| 11 |
|
Arminia Bielefeld | 25 | 8 | 7 | 10 | 35:40 | -5 | 31 |
| 12 |
|
SpVgg Greuther Fürth | 25 | 7 | 9 | 9 | 24:41 | -17 | 30 |
| 13 |
|
SV Darmstadt 98 | 25 | 8 | 5 | 12 | 34:43 | -9 | 29 |
| 14 |
|
Dynamo Dresden | 25 | 7 | 7 | 11 | 28:37 | -9 | 28 |
| 15 |
|
1. FC Magdeburg | 25 | 4 | 10 | 11 | 27:40 | -13 | 22 |
| 16 |
|
MSV Duisburg | 25 | 5 | 6 | 14 | 24:42 | -18 | 21 |
| 17 |
|
SV Sandhausen | 25 | 4 | 8 | 13 | 25:38 | -13 | 20 |
| 18 |
|
FC Ingolstadt 04 | 25 | 4 | 7 | 14 | 24:42 | -18 | 19 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
