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| 21.10.2022 | 18:30 | SV Darmstadt 98 | - | Holstein Kiel | 1:1 (0:1) | |
| 18:30 | Hansa Rostock | - | 1. FC Kaiserslautern | 0:2 (0:0) | ||
| 22.10.2022 | 13:00 | 1. FC Nürnberg | - | Hannover 96 | 0:0 (0:0) | |
| 13:00 | Jahn Regensburg | - | SV Sandhausen | 2:1 (1:1) | ||
| 13:00 | Eintracht Braunschweig | - | SC Paderborn 07 | 0:0 (0:0) | ||
| 20:30 | Arminia Bielefeld | - | FC St. Pauli | 2:0 (0:0) | ||
| 23.10.2022 | 13:30 | Hamburger SV | - | 1. FC Magdeburg | 2:3 (0:1) | |
| 13:30 | 1. FC Heidenheim 1846 | - | SpVgg Greuther Fürth | 3:1 (2:0) | ||
| 13:30 | Karlsruher SC | - | Fortuna Düsseldorf | 0:2 (0:2) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SV Darmstadt 98 | 13 | 8 | 4 | 1 | 23:13 | 10 | 28 |
| 2 |
|
SC Paderborn 07 | 13 | 8 | 2 | 3 | 32:12 | 20 | 26 |
| 3 |
|
Hamburger SV | 13 | 8 | 1 | 4 | 19:13 | 6 | 25 |
| 4 |
|
1. FC Heidenheim 1846 | 13 | 6 | 5 | 2 | 20:12 | 8 | 23 |
| 5 |
|
Hannover 96 | 13 | 6 | 3 | 4 | 21:16 | 5 | 21 |
| 6 |
|
Fortuna Düsseldorf | 13 | 6 | 2 | 5 | 22:15 | 7 | 20 |
| 7 |
|
Holstein Kiel | 13 | 5 | 5 | 3 | 24:24 | 0 | 20 |
| 8 |
|
1. FC Kaiserslautern (N) | 13 | 4 | 7 | 2 | 22:20 | 2 | 19 |
| 9 |
|
Jahn Regensburg | 13 | 5 | 3 | 5 | 14:18 | -4 | 18 |
| 10 |
|
Karlsruher SC | 13 | 5 | 2 | 6 | 21:19 | 2 | 17 |
| 11 |
|
Eintracht Braunschweig (N) | 13 | 4 | 4 | 5 | 15:21 | -6 | 16 |
| 12 |
|
FC St. Pauli | 13 | 3 | 5 | 5 | 18:19 | -1 | 14 |
| 13 |
|
1. FC Nürnberg | 13 | 4 | 2 | 7 | 12:21 | -9 | 14 |
|
Hansa Rostock | 13 | 4 | 2 | 7 | 12:21 | -9 | 14 | |
| 15 |
|
1. FC Magdeburg (N) | 13 | 4 | 1 | 8 | 16:27 | -11 | 13 |
| 16 |
|
SV Sandhausen | 13 | 3 | 3 | 7 | 13:19 | -6 | 12 |
| 17 |
|
Arminia Bielefeld (A) | 13 | 3 | 2 | 8 | 16:23 | -7 | 11 |
| 18 |
|
SpVgg Greuther Fürth (A) | 13 | 1 | 7 | 5 | 18:25 | -7 | 10 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
