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| 07.02.1981 | 15:30 | 1. FC Kaiserslautern | - | Hamburger SV | 2:2 (2:1) | |
| 15:30 | 1. FC Köln | - | VfB Stuttgart | 3:1 (2:1) | ||
| 15:30 | Eintracht Frankfurt | - | SV Bayer 04 Leverkusen | 2:0 (2:0) | ||
| 15:30 | Bor. Mönchengladbach | - | Arminia Bielefeld | 4:2 (1:1) | ||
| 15:30 | Bayer 05 Uerdingen | - | FC Schalke 04 | 1:3 (1:1) | ||
| 15:30 | Bayern München | - | Fortuna Düsseldorf | 3:2 (2:0) | ||
| 15:30 | MSV Duisburg | - | VfL Bochum | 0:3 (0:1) | ||
| 15:30 | Borussia Dortmund | - | Karlsruher SC | 3:3 (3:3) | ||
| 28.02.1981 | 15:30 | 1. FC Nürnberg | - | TSV 1860 München | 1:2 (0:1) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Hamburger SV | 20 | 14 | 3 | 3 | 48:23 | 25 | 31:9 |
| 2 |
|
Bayern München | 20 | 13 | 5 | 2 | 48:26 | 22 | 31:9 |
| 3 |
|
1. FC Kaiserslautern | 20 | 11 | 4 | 5 | 40:24 | 16 | 26:14 |
| 4 |
|
VfB Stuttgart | 20 | 10 | 5 | 5 | 40:28 | 12 | 25:15 |
| 5 |
|
Eintracht Frankfurt | 20 | 10 | 4 | 6 | 39:33 | 6 | 24:16 |
| 6 |
|
1. FC Köln | 20 | 8 | 6 | 6 | 36:31 | 5 | 22:18 |
| 7 |
|
Borussia Dortmund | 20 | 8 | 5 | 7 | 42:35 | 7 | 21:19 |
| 8 |
|
VfL Bochum | 20 | 5 | 10 | 5 | 31:28 | 3 | 20:20 |
| 9 |
|
MSV Duisburg | 20 | 6 | 7 | 7 | 28:32 | -4 | 19:21 |
| 10 |
|
Bor. Mönchengladbach | 20 | 7 | 5 | 8 | 32:40 | -8 | 19:21 |
| 11 |
|
Karlsruher SC | 20 | 4 | 10 | 6 | 28:38 | -10 | 18:22 |
| 12 |
|
SV Bayer 04 Leverkusen | 20 | 4 | 9 | 7 | 28:29 | -1 | 17:23 |
| 13 |
|
1. FC Nürnberg | 20 | 6 | 4 | 10 | 32:34 | -2 | 16:24 |
| 14 |
|
Fortuna Düsseldorf | 20 | 5 | 6 | 9 | 35:43 | -8 | 16:24 |
| 15 |
|
TSV 1860 München | 20 | 6 | 4 | 10 | 30:40 | -10 | 16:24 |
| 16 |
|
Bayer 05 Uerdingen | 20 | 5 | 5 | 10 | 30:40 | -10 | 15:25 |
| 17 |
|
FC Schalke 04 | 20 | 5 | 4 | 11 | 29:55 | -26 | 14:26 |
| 18 |
|
Arminia Bielefeld | 20 | 2 | 6 | 12 | 26:43 | -17 | 10:30 |
