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| 14.02.1981 | 15:30 | FC Schalke 04 | - | Bayern München | 2:2 (1:0) | |
| 15:30 | SV Bayer 04 Leverkusen | - | Bor. Mönchengladbach | 1:5 (0:1) | ||
| 15:30 | VfB Stuttgart | - | Eintracht Frankfurt | 1:1 (1:0) | ||
| 15:30 | Hamburger SV | - | 1. FC Köln | 2:0 (1:0) | ||
| 15:30 | TSV 1860 München | - | 1. FC Kaiserslautern | 1:1 (0:1) | ||
| 15:30 | VfL Bochum | - | 1. FC Nürnberg | 4:0 (1:0) | ||
| 15:30 | Karlsruher SC | - | MSV Duisburg | 2:0 (2:0) | ||
| 15:30 | Fortuna Düsseldorf | - | Borussia Dortmund | 2:2 (1:0) | ||
| 15:30 | Arminia Bielefeld | - | Bayer 05 Uerdingen | 3:1 (1:1) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Hamburger SV | 21 | 15 | 3 | 3 | 50:23 | 27 | 33:9 |
| 2 |
|
Bayern München | 21 | 13 | 6 | 2 | 50:28 | 22 | 32:10 |
| 3 |
|
1. FC Kaiserslautern | 21 | 11 | 5 | 5 | 41:25 | 16 | 27:15 |
| 4 |
|
VfB Stuttgart | 21 | 10 | 6 | 5 | 41:29 | 12 | 26:16 |
| 5 |
|
Eintracht Frankfurt | 21 | 10 | 5 | 6 | 40:34 | 6 | 25:17 |
| 6 |
|
Borussia Dortmund | 21 | 8 | 6 | 7 | 44:37 | 7 | 22:20 |
| 7 |
|
VfL Bochum | 21 | 6 | 10 | 5 | 35:28 | 7 | 22:20 |
| 8 |
|
1. FC Köln | 21 | 8 | 6 | 7 | 36:33 | 3 | 22:20 |
| 9 |
|
Bor. Mönchengladbach | 21 | 8 | 5 | 8 | 37:41 | -4 | 21:21 |
| 10 |
|
Karlsruher SC | 21 | 5 | 10 | 6 | 30:38 | -8 | 20:22 |
| 11 |
|
MSV Duisburg | 21 | 6 | 7 | 8 | 28:34 | -6 | 19:23 |
| 12 |
|
SV Bayer 04 Leverkusen | 21 | 4 | 9 | 8 | 29:34 | -5 | 17:25 |
| 13 |
|
Fortuna Düsseldorf | 21 | 5 | 7 | 9 | 37:45 | -8 | 17:25 |
| 14 |
|
TSV 1860 München | 21 | 6 | 5 | 10 | 31:41 | -10 | 17:25 |
| 15 |
|
1. FC Nürnberg | 21 | 6 | 4 | 11 | 32:38 | -6 | 16:26 |
| 16 |
|
Bayer 05 Uerdingen | 21 | 5 | 5 | 11 | 31:43 | -12 | 15:27 |
| 17 |
|
FC Schalke 04 | 21 | 5 | 5 | 11 | 31:57 | -26 | 15:27 |
| 18 |
|
Arminia Bielefeld | 21 | 3 | 6 | 12 | 29:44 | -15 | 12:30 |
