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| 15.10.2021 | 21:00 | West Bromwich Albion | - | Birmingham City | 1:0 (0:0) | |
| 16.10.2021 | 13:30 | Fulham FC | - | Queens Park Rangers | 4:1 (1:0) | |
| 16:00 | Blackburn Rovers | - | Coventry City | 2:2 (2:0) | ||
| 16:00 | Bristol City | - | AFC Bournemouth | 0:2 (0:2) | ||
| 16:00 | Middlesbrough FC | - | Peterborough United | 2:0 (0:0) | ||
| 16:00 | Millwall FC | - | Luton Town | 0:2 (0:1) | ||
| 16:00 | Reading FC | - | Barnsley FC | 1:0 (0:0) | ||
| 16:00 | Huddersfield Town | - | Hull City | 2:0 (1:0) | ||
| 16:00 | Nottingham Forest | - | Blackpool FC | 2:1 (1:0) | ||
| 16:00 | Preston North End | - | Derby County | 0:0 (0:0) | ||
| 16:00 | Sheffield United | - | Stoke City | 2:1 (0:0) | ||
| 17.10.2021 | 13:00 | Swansea City | - | Cardiff City | 3:0 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
AFC Bournemouth | 12 | 8 | 4 | 0 | 20:8 | 12 | 28 |
| 2 |
|
West Bromwich Albion | 12 | 7 | 4 | 1 | 21:9 | 12 | 25 |
| 3 |
|
Fulham FC | 12 | 7 | 2 | 3 | 27:14 | 13 | 23 |
| 4 |
|
Coventry City | 12 | 7 | 2 | 3 | 18:14 | 4 | 23 |
| 5 |
|
Stoke City | 12 | 6 | 3 | 3 | 16:13 | 3 | 21 |
| 6 |
|
Huddersfield Town | 12 | 6 | 2 | 4 | 18:14 | 4 | 20 |
| 7 |
|
Queens Park Rangers | 12 | 5 | 3 | 4 | 23:20 | 3 | 18 |
| 8 |
|
Blackburn Rovers | 12 | 4 | 5 | 3 | 21:16 | 5 | 17 |
| 9 |
|
Luton Town | 12 | 4 | 5 | 3 | 20:16 | 4 | 17 |
| 10 |
|
Bristol City | 12 | 4 | 4 | 4 | 14:15 | -1 | 16 |
| 11 |
|
Middlesbrough FC | 12 | 4 | 3 | 5 | 13:13 | 0 | 15 |
| 12 |
|
Sheffield United | 12 | 4 | 3 | 5 | 16:17 | -1 | 15 |
| 13 |
|
Millwall FC | 12 | 3 | 6 | 3 | 11:13 | -2 | 15 |
| 14 |
|
Blackpool FC | 12 | 4 | 3 | 5 | 12:16 | -4 | 15 |
| 15 |
|
Nottingham Forest | 12 | 4 | 2 | 6 | 16:15 | 1 | 14 |
| 16 |
|
Swansea City | 12 | 3 | 5 | 4 | 12:14 | -2 | 14 |
| 17 |
|
Reading FC | 12 | 6 | 1 | 5 | 18:19 | -1 | 13 |
| 18 |
|
Preston North End | 12 | 2 | 6 | 4 | 12:15 | -3 | 12 |
| 19 |
|
Birmingham City | 12 | 3 | 3 | 6 | 10:16 | -6 | 12 |
| 20 |
|
Cardiff City | 12 | 3 | 2 | 7 | 12:22 | -10 | 11 |
| 21 |
|
Hull City | 12 | 2 | 3 | 7 | 8:17 | -9 | 9 |
| 22 |
|
Barnsley FC | 12 | 1 | 5 | 6 | 7:15 | -8 | 8 |
| 23 |
|
Peterborough United | 12 | 2 | 2 | 8 | 12:25 | -13 | 8 |
| 24 |
|
Derby County | 12 | 3 | 6 | 3 | 7:8 | -1 | -6 |
| Promotie | |
| Play-offs | |
| Degradatie |
