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| 23.10.2021 | 13:30 | Cardiff City | - | Middlesbrough FC | 0:2 (0:1) | |
| 16:00 | AFC Bournemouth | - | Huddersfield Town | 3:0 (2:0) | ||
| 16:00 | Birmingham City | - | Swansea City | 2:1 (0:0) | ||
| 16:00 | Blackburn Rovers | - | Reading FC | 2:0 (0:0) | ||
| 16:00 | Blackpool FC | - | Preston North End | 2:0 (1:0) | ||
| 16:00 | Coventry City | - | Derby County | 1:1 (1:0) | ||
| 16:00 | Millwall FC | - | Stoke City | 2:1 (0:1) | ||
| 16:00 | Luton Town | - | Hull City | 1:0 (1:0) | ||
| 16:00 | Peterborough United | - | Queens Park Rangers | 2:1 (0:0) | ||
| 16:00 | West Bromwich Albion | - | Bristol City | 3:0 (2:0) | ||
| 24.10.2021 | 13:30 | Barnsley FC | - | Sheffield United | 2:3 (0:0) | |
| 16:00 | Nottingham Forest | - | Fulham FC | 0:4 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
AFC Bournemouth | 14 | 10 | 4 | 0 | 24:8 | 16 | 34 |
| 2 |
|
Fulham FC | 14 | 9 | 2 | 3 | 33:14 | 19 | 29 |
| 3 |
|
West Bromwich Albion | 14 | 8 | 4 | 2 | 25:11 | 14 | 28 |
| 4 |
|
Coventry City | 14 | 7 | 3 | 4 | 20:17 | 3 | 24 |
| 5 |
|
Luton Town | 14 | 5 | 6 | 3 | 23:18 | 5 | 21 |
| 6 |
|
Middlesbrough FC | 14 | 6 | 3 | 5 | 17:13 | 4 | 21 |
| 7 |
|
Queens Park Rangers | 14 | 6 | 3 | 5 | 25:22 | 3 | 21 |
| 8 |
|
Huddersfield Town | 14 | 6 | 3 | 5 | 18:17 | 1 | 21 |
| 9 |
|
Stoke City | 14 | 6 | 3 | 5 | 17:16 | 1 | 21 |
| 10 |
|
Millwall FC | 14 | 5 | 6 | 3 | 15:15 | 0 | 21 |
| 11 |
|
Blackpool FC | 14 | 6 | 3 | 5 | 17:18 | -1 | 21 |
| 12 |
|
Blackburn Rovers | 14 | 5 | 5 | 4 | 23:17 | 6 | 20 |
| 13 |
|
Sheffield United | 14 | 5 | 3 | 6 | 20:21 | -1 | 18 |
| 14 |
|
Nottingham Forest | 14 | 5 | 2 | 7 | 18:20 | -2 | 17 |
| 15 |
|
Swansea City | 14 | 4 | 5 | 5 | 15:17 | -2 | 17 |
| 16 |
|
Bristol City | 14 | 4 | 4 | 6 | 15:20 | -5 | 16 |
| 17 |
|
Birmingham City | 14 | 4 | 4 | 6 | 12:17 | -5 | 16 |
| 18 |
|
Preston North End | 14 | 3 | 6 | 5 | 14:18 | -4 | 15 |
| 19 |
|
Peterborough United | 14 | 4 | 2 | 8 | 16:27 | -11 | 14 |
| 20 |
|
Reading FC | 14 | 6 | 1 | 7 | 20:24 | -4 | 13 |
| 21 |
|
Cardiff City | 14 | 3 | 2 | 9 | 12:26 | -14 | 11 |
| 22 |
|
Hull City | 14 | 2 | 3 | 9 | 9:20 | -11 | 9 |
| 23 |
|
Barnsley FC | 14 | 1 | 5 | 8 | 9:20 | -11 | 8 |
| 24 |
|
Derby County | 14 | 3 | 8 | 3 | 10:11 | -1 | -4 |
| Promotie | |
| Play-offs | |
| Degradatie |
