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| 11.02.2011 | 18:00 | Rot-Weiß Oberhausen | - | SC Paderborn 07 | 2:0 (1:0) | |
| 18:00 | 1. FC Union Berlin | - | VfL Osnabrück | 3:3 (0:1) | ||
| 20:30 | FC Augsburg | - | MSV Duisburg | 0:0 (0:0) | ||
| 12.02.2011 | 13:00 | SpVgg Greuther Fürth | - | Energie Cottbus | 3:1 (1:0) | |
| 13:00 | Alemannia Aachen | - | FSV Frankfurt | 2:1 (1:0) | ||
| 13.02.2011 | 13:30 | Arminia Bielefeld | - | VfL Bochum | 2:2 (1:1) | |
| 13:30 | Karlsruher SC | - | Hertha BSC | 2:6 (1:0) | ||
| 13:30 | Fortuna Düsseldorf | - | FC Ingolstadt 04 | 3:1 (1:0) | ||
| 14.02.2011 | 20:15 | Erzgebirge Aue | - | TSV 1860 München | 1:0 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Hertha BSC | 22 | 14 | 3 | 5 | 42:21 | 21 | 45 |
| 2 |
|
FC Augsburg | 22 | 12 | 5 | 5 | 39:18 | 21 | 41 |
| 3 |
|
VfL Bochum | 22 | 13 | 2 | 7 | 31:25 | 6 | 41 |
| 4 |
|
Erzgebirge Aue | 22 | 12 | 4 | 6 | 25:25 | 0 | 40 |
| 5 |
|
MSV Duisburg | 22 | 11 | 6 | 5 | 37:20 | 17 | 39 |
| 6 |
|
SpVgg Greuther Fürth | 22 | 11 | 6 | 5 | 32:18 | 14 | 39 |
| 7 |
|
Energie Cottbus | 22 | 10 | 5 | 7 | 42:34 | 8 | 35 |
| 8 |
|
FSV Frankfurt | 22 | 10 | 3 | 9 | 32:30 | 2 | 33 |
| 9 |
|
Fortuna Düsseldorf | 22 | 10 | 2 | 10 | 29:25 | 4 | 32 |
| 10 |
|
Alemannia Aachen | 22 | 8 | 8 | 6 | 37:34 | 3 | 32 |
| 11 |
|
TSV 1860 München | 22 | 8 | 8 | 6 | 26:23 | 3 | 30 |
| 12 |
|
SC Paderborn 07 | 22 | 8 | 4 | 10 | 22:26 | -4 | 28 |
| 13 |
|
1. FC Union Berlin | 22 | 7 | 5 | 10 | 25:30 | -5 | 26 |
| 14 |
|
VfL Osnabrück | 22 | 6 | 4 | 12 | 30:41 | -11 | 22 |
| 15 |
|
Rot-Weiß Oberhausen | 22 | 6 | 4 | 12 | 19:38 | -19 | 22 |
| 16 |
|
Karlsruher SC | 22 | 5 | 5 | 12 | 28:48 | -20 | 20 |
| 17 |
|
FC Ingolstadt 04 | 22 | 4 | 5 | 13 | 23:35 | -12 | 17 |
| 18 |
|
Arminia Bielefeld | 22 | 2 | 3 | 17 | 17:45 | -28 | 6 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
