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| 18.02.2011 | 18:00 | TSV 1860 München | - | FC Augsburg | 0:2 (0:1) | |
| 18:00 | VfL Bochum | - | Fortuna Düsseldorf | 2:0 (1:0) | ||
| 18:00 | FC Ingolstadt 04 | - | SpVgg Greuther Fürth | 0:2 (0:1) | ||
| 19.02.2011 | 13:00 | MSV Duisburg | - | 1. FC Union Berlin | 0:1 (0:1) | |
| 13:00 | SC Paderborn 07 | - | Alemannia Aachen | 1:3 (1:2) | ||
| 20.02.2011 | 13:30 | Erzgebirge Aue | - | Arminia Bielefeld | 3:0 (2:0) | |
| 13:30 | FSV Frankfurt | - | Karlsruher SC | 1:2 (1:1) | ||
| 13:30 | VfL Osnabrück | - | Rot-Weiß Oberhausen | 3:1 (2:1) | ||
| 21.02.2011 | 20:15 | Hertha BSC | - | Energie Cottbus | 2:2 (2:2) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Hertha BSC | 23 | 14 | 4 | 5 | 44:23 | 21 | 46 |
| 2 |
|
FC Augsburg | 23 | 13 | 5 | 5 | 41:18 | 23 | 44 |
| 3 |
|
VfL Bochum | 23 | 14 | 2 | 7 | 33:25 | 8 | 44 |
| 4 |
|
Erzgebirge Aue | 23 | 13 | 4 | 6 | 28:25 | 3 | 43 |
| 5 |
|
SpVgg Greuther Fürth | 23 | 12 | 6 | 5 | 34:18 | 16 | 42 |
| 6 |
|
MSV Duisburg | 23 | 11 | 6 | 6 | 37:21 | 16 | 39 |
| 7 |
|
Energie Cottbus | 23 | 10 | 6 | 7 | 44:36 | 8 | 36 |
| 8 |
|
Alemannia Aachen | 23 | 9 | 8 | 6 | 40:35 | 5 | 35 |
| 9 |
|
FSV Frankfurt | 23 | 10 | 3 | 10 | 33:32 | 1 | 33 |
| 10 |
|
Fortuna Düsseldorf | 23 | 10 | 2 | 11 | 29:27 | 2 | 32 |
| 11 |
|
TSV 1860 München | 23 | 8 | 8 | 7 | 26:25 | 1 | 30 |
| 12 |
|
1. FC Union Berlin | 23 | 8 | 5 | 10 | 26:30 | -4 | 29 |
| 13 |
|
SC Paderborn 07 | 23 | 8 | 4 | 11 | 23:29 | -6 | 28 |
| 14 |
|
VfL Osnabrück | 23 | 7 | 4 | 12 | 33:42 | -9 | 25 |
| 15 |
|
Karlsruher SC | 23 | 6 | 5 | 12 | 30:49 | -19 | 23 |
| 16 |
|
Rot-Weiß Oberhausen | 23 | 6 | 4 | 13 | 20:41 | -21 | 22 |
| 17 |
|
FC Ingolstadt 04 | 23 | 4 | 5 | 14 | 23:37 | -14 | 17 |
| 18 |
|
Arminia Bielefeld | 23 | 2 | 3 | 18 | 17:48 | -31 | 6 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
