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| 12.02.2016 | 18:30 | SC Paderborn 07 | - | 1. FC Kaiserslautern | 0:4 (0:2) | |
| 18:30 | FC St. Pauli | - | RB Leipzig | 1:0 (1:0) | ||
| 18:30 | FSV Frankfurt | - | SpVgg Greuther Fürth | 1:2 (0:2) | ||
| 13.02.2016 | 13:00 | MSV Duisburg | - | Karlsruher SC | 0:1 (0:1) | |
| 13:00 | 1. FC Heidenheim 1846 | - | SV Sandhausen | 1:1 (1:0) | ||
| 14.02.2016 | 13:30 | SC Freiburg | - | Fortuna Düsseldorf | 1:2 (1:1) | |
| 13:30 | 1. FC Union Berlin | - | TSV 1860 München | 3:0 (1:0) | ||
| 13:30 | Eintracht Braunschweig | - | Arminia Bielefeld | 1:0 (1:0) | ||
| 15.02.2016 | 20:15 | 1. FC Nürnberg | - | VfL Bochum | 1:1 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RB Leipzig | 21 | 13 | 5 | 3 | 33:19 | 14 | 44 |
| 2 |
|
SC Freiburg | 21 | 11 | 5 | 5 | 44:26 | 18 | 38 |
| 3 |
|
1. FC Nürnberg | 21 | 10 | 7 | 4 | 40:28 | 12 | 37 |
| 4 |
|
FC St. Pauli | 21 | 10 | 6 | 5 | 25:20 | 5 | 36 |
| 5 |
|
VfL Bochum | 21 | 8 | 8 | 5 | 31:19 | 12 | 32 |
| 6 |
|
Eintracht Braunschweig | 21 | 9 | 5 | 7 | 28:17 | 11 | 32 |
| 7 |
|
SV Sandhausen | 21 | 9 | 6 | 6 | 29:24 | 5 | 30 |
| 8 |
|
1. FC Kaiserslautern | 21 | 8 | 6 | 7 | 30:26 | 4 | 30 |
| 9 |
|
Karlsruher SC | 21 | 8 | 5 | 8 | 21:26 | -5 | 29 |
| 10 |
|
1. FC Heidenheim 1846 | 21 | 7 | 7 | 7 | 23:21 | 2 | 28 |
| 11 |
|
SpVgg Greuther Fürth | 21 | 8 | 4 | 9 | 27:35 | -8 | 28 |
| 12 |
|
1. FC Union Berlin | 21 | 6 | 9 | 6 | 36:32 | 4 | 27 |
| 13 |
|
Arminia Bielefeld | 21 | 5 | 12 | 4 | 19:18 | 1 | 27 |
| 14 |
|
Fortuna Düsseldorf | 21 | 6 | 5 | 10 | 17:26 | -9 | 23 |
| 15 |
|
FSV Frankfurt | 21 | 6 | 5 | 10 | 20:30 | -10 | 23 |
| 16 |
|
SC Paderborn 07 | 21 | 4 | 5 | 12 | 17:38 | -21 | 17 |
| 17 |
|
TSV 1860 München | 21 | 2 | 8 | 11 | 15:30 | -15 | 14 |
| 18 |
|
MSV Duisburg | 21 | 2 | 6 | 13 | 16:36 | -20 | 12 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
