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| 19.02.2016 | 18:30 | RB Leipzig | - | 1. FC Union Berlin | 3:0 (2:0) | |
| 18:30 | FC St. Pauli | - | FSV Frankfurt | 1:3 (1:2) | ||
| 18:30 | SpVgg Greuther Fürth | - | MSV Duisburg | 1:1 (0:0) | ||
| 20.02.2016 | 13:00 | Karlsruher SC | - | Eintracht Braunschweig | 2:2 (1:1) | |
| 13:00 | 1. FC Kaiserslautern | - | 1. FC Heidenheim 1846 | 2:2 (0:1) | ||
| 21.02.2016 | 13:30 | SV Sandhausen | - | SC Freiburg | 0:2 (0:0) | |
| 13:30 | Arminia Bielefeld | - | SC Paderborn 07 | 1:1 (0:1) | ||
| 13:30 | TSV 1860 München | - | VfL Bochum | 1:1 (1:1) | ||
| 22.02.2016 | 20:15 | Fortuna Düsseldorf | - | 1. FC Nürnberg | 1:1 (1:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RB Leipzig | 22 | 14 | 5 | 3 | 36:19 | 17 | 47 |
| 2 |
|
SC Freiburg | 22 | 12 | 5 | 5 | 46:26 | 20 | 41 |
| 3 |
|
1. FC Nürnberg | 22 | 10 | 8 | 4 | 41:29 | 12 | 38 |
| 4 |
|
FC St. Pauli | 22 | 10 | 6 | 6 | 26:23 | 3 | 36 |
| 5 |
|
VfL Bochum | 22 | 8 | 9 | 5 | 32:20 | 12 | 33 |
| 6 |
|
Eintracht Braunschweig | 22 | 9 | 6 | 7 | 30:19 | 11 | 33 |
| 7 |
|
1. FC Kaiserslautern | 22 | 8 | 7 | 7 | 32:28 | 4 | 31 |
| 8 |
|
SV Sandhausen | 22 | 9 | 6 | 7 | 29:26 | 3 | 30 |
| 9 |
|
Karlsruher SC | 22 | 8 | 6 | 8 | 23:28 | -5 | 30 |
| 10 |
|
1. FC Heidenheim 1846 | 22 | 7 | 8 | 7 | 25:23 | 2 | 29 |
| 11 |
|
SpVgg Greuther Fürth | 22 | 8 | 5 | 9 | 28:36 | -8 | 29 |
| 12 |
|
Arminia Bielefeld | 22 | 5 | 13 | 4 | 20:19 | 1 | 28 |
| 13 |
|
1. FC Union Berlin | 22 | 6 | 9 | 7 | 36:35 | 1 | 27 |
| 14 |
|
FSV Frankfurt | 22 | 7 | 5 | 10 | 23:31 | -8 | 26 |
| 15 |
|
Fortuna Düsseldorf | 22 | 6 | 6 | 10 | 18:27 | -9 | 24 |
| 16 |
|
SC Paderborn 07 | 22 | 4 | 6 | 12 | 18:39 | -21 | 18 |
| 17 |
|
TSV 1860 München | 22 | 2 | 9 | 11 | 16:31 | -15 | 15 |
| 18 |
|
MSV Duisburg | 22 | 2 | 7 | 13 | 17:37 | -20 | 13 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
