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| 04.03.2016 | 18:30 | Fortuna Düsseldorf | - | Karlsruher SC | 0:1 (0:0) | |
| 18:30 | TSV 1860 München | - | SV Sandhausen | 3:2 (2:1) | ||
| 20:30 | 1. FC Nürnberg | - | 1. FC Kaiserslautern | 2:1 (1:1) | ||
| 05.03.2016 | 13:00 | SC Paderborn 07 | - | SpVgg Greuther Fürth | 1:1 (1:0) | |
| 13:00 | 1. FC Union Berlin | - | FSV Frankfurt | 4:0 (3:0) | ||
| 06.03.2016 | 13:30 | 1. FC Heidenheim 1846 | - | FC St. Pauli | 2:0 (0:0) | |
| 13:30 | VfL Bochum | - | Arminia Bielefeld | 2:2 (1:0) | ||
| 13:30 | Eintracht Braunschweig | - | MSV Duisburg | 1:1 (0:0) | ||
| 07.03.2016 | 20:15 | SC Freiburg | - | RB Leipzig | 2:1 (1:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RB Leipzig | 25 | 16 | 5 | 4 | 41:22 | 19 | 53 |
| 2 |
|
SC Freiburg | 25 | 15 | 5 | 5 | 54:28 | 26 | 50 |
| 3 |
|
1. FC Nürnberg | 25 | 13 | 8 | 4 | 47:31 | 16 | 47 |
| 4 |
|
FC St. Pauli | 25 | 12 | 6 | 7 | 29:25 | 4 | 42 |
| 5 |
|
VfL Bochum | 25 | 10 | 10 | 5 | 40:25 | 15 | 40 |
| 6 |
|
Eintracht Braunschweig | 25 | 9 | 8 | 8 | 31:21 | 10 | 35 |
| 7 |
|
1. FC Heidenheim 1846 | 25 | 9 | 8 | 8 | 31:28 | 3 | 35 |
| 8 |
|
Karlsruher SC | 25 | 9 | 7 | 9 | 25:30 | -5 | 34 |
| 9 |
|
1. FC Union Berlin | 25 | 8 | 9 | 8 | 42:38 | 4 | 33 |
| 10 |
|
SpVgg Greuther Fürth | 25 | 9 | 6 | 10 | 32:39 | -7 | 33 |
| 11 |
|
1. FC Kaiserslautern | 25 | 8 | 7 | 10 | 33:33 | 0 | 31 |
| 12 |
|
SV Sandhausen | 25 | 9 | 6 | 10 | 33:34 | -1 | 30 |
| 13 |
|
Arminia Bielefeld | 25 | 5 | 14 | 6 | 25:28 | -3 | 29 |
| 14 |
|
FSV Frankfurt | 25 | 7 | 7 | 11 | 26:38 | -12 | 28 |
| 15 |
|
TSV 1860 München | 25 | 5 | 9 | 11 | 23:35 | -12 | 24 |
| 16 |
|
Fortuna Düsseldorf | 25 | 6 | 6 | 13 | 21:34 | -13 | 24 |
| 17 |
|
SC Paderborn 07 | 25 | 4 | 8 | 13 | 19:41 | -22 | 20 |
| 18 |
|
MSV Duisburg | 25 | 2 | 9 | 14 | 21:43 | -22 | 15 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
