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| 08.04.2016 | 18:30 | 1. FC Heidenheim 1846 | - | Eintracht Braunschweig | 2:2 (0:2) | |
| 18:30 | SC Paderborn 07 | - | 1. FC Union Berlin | 0:4 (0:4) | ||
| 18:30 | TSV 1860 München | - | SpVgg Greuther Fürth | 0:1 (0:1) | ||
| 09.04.2016 | 13:00 | VfL Bochum | - | FSV Frankfurt | 4:1 (2:1) | |
| 13:00 | SV Sandhausen | - | Arminia Bielefeld | 1:4 (1:1) | ||
| 10.04.2016 | 13:30 | 1. FC Kaiserslautern | - | Karlsruher SC | 0:0 (0:0) | |
| 13:30 | SC Freiburg | - | FC St. Pauli | 4:3 (2:0) | ||
| 13:30 | 1. FC Nürnberg | - | MSV Duisburg | 1:2 (0:1) | ||
| 11.04.2016 | 20:15 | Fortuna Düsseldorf | - | RB Leipzig | 1:3 (1:1) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SC Freiburg | 29 | 19 | 5 | 5 | 65:34 | 31 | 62 |
| 2 |
|
RB Leipzig | 29 | 19 | 5 | 5 | 50:28 | 22 | 62 |
| 3 |
|
1. FC Nürnberg | 29 | 16 | 8 | 5 | 58:34 | 24 | 56 |
| 4 |
|
VfL Bochum | 29 | 12 | 11 | 6 | 49:31 | 18 | 47 |
| 5 |
|
FC St. Pauli | 29 | 13 | 7 | 9 | 37:33 | 4 | 46 |
| 6 |
|
1. FC Heidenheim 1846 | 29 | 10 | 11 | 8 | 37:32 | 5 | 41 |
| 7 |
|
1. FC Union Berlin | 29 | 10 | 10 | 9 | 50:41 | 9 | 40 |
| 8 |
|
SpVgg Greuther Fürth | 29 | 11 | 7 | 11 | 40:44 | -4 | 40 |
| 9 |
|
Eintracht Braunschweig | 29 | 10 | 9 | 10 | 36:30 | 6 | 39 |
| 10 |
|
Karlsruher SC | 29 | 10 | 9 | 10 | 28:32 | -4 | 39 |
| 11 |
|
1. FC Kaiserslautern | 29 | 9 | 8 | 12 | 38:39 | -1 | 35 |
| 12 |
|
Arminia Bielefeld | 29 | 6 | 16 | 7 | 30:34 | -4 | 34 |
| 13 |
|
SV Sandhausen | 29 | 10 | 6 | 13 | 35:42 | -7 | 33 |
| 14 |
|
FSV Frankfurt | 29 | 7 | 8 | 14 | 30:50 | -20 | 29 |
| 15 |
|
Fortuna Düsseldorf | 29 | 7 | 7 | 15 | 26:41 | -15 | 28 |
| 16 |
|
TSV 1860 München | 29 | 5 | 10 | 14 | 26:42 | -16 | 25 |
| 17 |
|
SC Paderborn 07 | 29 | 5 | 9 | 15 | 24:50 | -26 | 24 |
| 18 |
|
MSV Duisburg | 29 | 4 | 10 | 15 | 25:47 | -22 | 22 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
