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| 15.04.2016 | 18:30 | FSV Frankfurt | - | SC Paderborn 07 | 0:2 (0:0) | |
| 18:30 | MSV Duisburg | - | TSV 1860 München | 2:1 (0:0) | ||
| 18:30 | RB Leipzig | - | SV Sandhausen | 0:1 (0:0) | ||
| 16.04.2016 | 13:00 | Karlsruher SC | - | 1. FC Nürnberg | 2:1 (1:1) | |
| 13:00 | FC St. Pauli | - | VfL Bochum | 2:0 (0:0) | ||
| 17.04.2016 | 13:30 | Arminia Bielefeld | - | 1. FC Kaiserslautern | 0:1 (0:0) | |
| 13:30 | SpVgg Greuther Fürth | - | Fortuna Düsseldorf | 3:1 (3:1) | ||
| 13:30 | 1. FC Union Berlin | - | 1. FC Heidenheim 1846 | 1:0 (1:0) | ||
| 18.04.2016 | 20:15 | Eintracht Braunschweig | - | SC Freiburg | 2:2 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SC Freiburg | 30 | 19 | 6 | 5 | 67:36 | 31 | 63 |
| 2 |
|
RB Leipzig | 30 | 19 | 5 | 6 | 50:29 | 21 | 62 |
| 3 |
|
1. FC Nürnberg | 30 | 16 | 8 | 6 | 59:36 | 23 | 56 |
| 4 |
|
FC St. Pauli | 30 | 14 | 7 | 9 | 39:33 | 6 | 49 |
| 5 |
|
VfL Bochum | 30 | 12 | 11 | 7 | 49:33 | 16 | 47 |
| 6 |
|
1. FC Union Berlin | 30 | 11 | 10 | 9 | 51:41 | 10 | 43 |
| 7 |
|
SpVgg Greuther Fürth | 30 | 12 | 7 | 11 | 43:45 | -2 | 43 |
| 8 |
|
Karlsruher SC | 30 | 11 | 9 | 10 | 30:33 | -3 | 42 |
| 9 |
|
1. FC Heidenheim 1846 | 30 | 10 | 11 | 9 | 37:33 | 4 | 41 |
| 10 |
|
Eintracht Braunschweig | 30 | 10 | 10 | 10 | 38:32 | 6 | 40 |
| 11 |
|
1. FC Kaiserslautern | 30 | 10 | 8 | 12 | 39:39 | 0 | 38 |
| 12 |
|
SV Sandhausen | 30 | 11 | 6 | 13 | 36:42 | -6 | 36 |
| 13 |
|
Arminia Bielefeld | 30 | 6 | 16 | 8 | 30:35 | -5 | 34 |
| 14 |
|
FSV Frankfurt | 30 | 7 | 8 | 15 | 30:52 | -22 | 29 |
| 15 |
|
Fortuna Düsseldorf | 30 | 7 | 7 | 16 | 27:44 | -17 | 28 |
| 16 |
|
SC Paderborn 07 | 30 | 6 | 9 | 15 | 26:50 | -24 | 27 |
| 17 |
|
TSV 1860 München | 30 | 5 | 10 | 15 | 27:44 | -17 | 25 |
| 18 |
|
MSV Duisburg | 30 | 5 | 10 | 15 | 27:48 | -21 | 25 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
