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|
| 08.04.2022 | 18:30 | Fortuna Düsseldorf | - | Hansa Rostock | 3:0 (1:0) | |
| 18:30 | Jahn Regensburg | - | FC Ingolstadt 04 | 1:1 (0:1) | ||
| 09.04.2022 | 13:30 | FC St. Pauli | - | Werder Bremen | 1:1 (1:0) | |
| 13:30 | FC Schalke 04 | - | 1. FC Heidenheim 1846 | 3:0 (1:0) | ||
| 13:30 | Erzgebirge Aue | - | Hannover 96 | 1:3 (0:2) | ||
| 20:30 | 1. FC Nürnberg | - | SV Darmstadt 98 | 3:1 (1:0) | ||
| 10.04.2022 | 13:30 | Holstein Kiel | - | Hamburger SV | 1:0 (1:0) | |
| 13:30 | SC Paderborn 07 | - | Karlsruher SC | 2:2 (1:1) | ||
| 13:30 | SV Sandhausen | - | Dynamo Dresden | 2:1 (1:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Schalke 04 | 29 | 16 | 5 | 8 | 59:34 | 25 | 53 |
| 2 |
|
Werder Bremen | 29 | 15 | 8 | 6 | 53:38 | 15 | 53 |
| 3 |
|
FC St. Pauli | 29 | 15 | 7 | 7 | 54:39 | 15 | 52 |
| 4 |
|
SV Darmstadt 98 | 29 | 15 | 6 | 8 | 57:38 | 19 | 51 |
| 5 |
|
1. FC Nürnberg | 29 | 14 | 7 | 8 | 44:38 | 6 | 49 |
| 6 |
|
Hamburger SV | 29 | 11 | 12 | 6 | 51:30 | 21 | 45 |
| 7 |
|
1. FC Heidenheim 1846 | 29 | 13 | 6 | 10 | 37:39 | -2 | 45 |
| 8 |
|
SC Paderborn 07 | 29 | 10 | 11 | 8 | 50:41 | 9 | 41 |
| 9 |
|
Karlsruher SC | 29 | 9 | 12 | 8 | 50:44 | 6 | 39 |
| 10 |
|
Jahn Regensburg | 29 | 10 | 8 | 11 | 46:41 | 5 | 38 |
| 11 |
|
Holstein Kiel | 29 | 10 | 7 | 12 | 38:48 | -10 | 37 |
| 12 |
|
Hansa Rostock | 29 | 10 | 7 | 12 | 36:46 | -10 | 37 |
| 13 |
|
Fortuna Düsseldorf | 29 | 9 | 9 | 11 | 38:36 | 2 | 36 |
| 14 |
|
Hannover 96 | 29 | 9 | 8 | 12 | 29:42 | -13 | 35 |
| 15 |
|
SV Sandhausen | 29 | 8 | 10 | 11 | 33:46 | -13 | 34 |
| 16 |
|
Dynamo Dresden | 29 | 7 | 7 | 15 | 28:40 | -12 | 28 |
| 17 |
|
FC Ingolstadt 04 | 29 | 4 | 7 | 18 | 26:55 | -29 | 19 |
| 18 |
|
Erzgebirge Aue | 29 | 4 | 7 | 18 | 27:61 | -34 | 19 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
