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| U | Vejle BK | - | FC Twente '65 | 0:3 (0:1) | ||
| R | FC Twente '65 | - | Vejle BK | 4:0 (3:0) | ||
| U: 01.03.1978 | R: 15.03.1978 | Winnaars: FC Twente '65 | ||||
| U | Austria Wien | - | Hajduk Split | 1:1 (0:0) | ||
| R | Hajduk Split | - | Austria Wien | 0:3 (1:0, 1:1, 1:1) d.p. | ||
| U: 02.03.1978 | R: 15.03.1978 | Winnaars: Austria Wien | ||||
| U | Real Betis | - | Dinamo Moskou | 0:0 (0:0) | ||
| R | Dinamo Moskou | - | Real Betis | 3:0 (0:0) | ||
| U: 02.03.1978 | R: 15.03.1978 | Winnaars: Dinamo Moskou | ||||
| U | FC Porto | - | RSC Anderlecht | 1:0 (1:0) | ||
| R | RSC Anderlecht | - | FC Porto | 3:0 (2:0) | ||
| U: 02.03.1978 | R: 15.03.1978 | Winnaars: RSC Anderlecht | ||||
