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| U | Olympique Lyon | - | ASD Torres Calcio | 3:0 (2:0) | ||
| R | ASD Torres Calcio | - | Olympique Lyon | 1:0 (1:0) | ||
| U: 10.03.2010 17:30 | R: 17.03.2010 15:00 | Winnaars: Olympique Lyon | ||||
| U | Umeå IK FF | - | Montpellier HSC | 0:0 (0:0) | ||
| R | Montpellier HSC | - | Umeå IK FF | 2:2 (0:0) | ||
| U: 10.03.2010 19:00 | R: 17.03.2010 19:00 | Winnaars: Umeå IK FF | ||||
| U | Turbine Potsdam | - | Røa IL | 5:0 (2:0) | ||
| R | Røa IL | - | Turbine Potsdam | 0:5 (0:1) | ||
| U: 10.03.2010 19:00 | R: 17.03.2010 15:30 | Winnaars: Turbine Potsdam | ||||
| U | FCR 2001 Duisburg | - | Arsenal LFC | 2:1 (1:0) | ||
| R | Arsenal LFC | - | FCR 2001 Duisburg | 0:2 (0:0) | ||
| U: 10.03.2010 19:30 | R: 14.03.2010 14:00 | Winnaars: FCR 2001 Duisburg | ||||
