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| U | FC Barcelona | - | VfL Wolfsburg | 5:1 (4:0) | ||
| R | VfL Wolfsburg | - | FC Barcelona | 2:0 (0:0) | ||
| U: 22.04.2022 18:45 | R: 30.04.2022 18:00 | Winnaars: FC Barcelona | ||||
| U | Olympique Lyon | - | Paris Saint-Germain | 3:2 (2:1) | ||
| R | Paris Saint-Germain | - | Olympique Lyon | 1:2 (0:1) | ||
| U: 24.04.2022 17:00 | R: 30.04.2022 21:00 | Winnaars: Olympique Lyon | ||||
