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| U | Fulham FC | - | VfL Wolfsburg | 2:1 (0:0) | ||
| R | VfL Wolfsburg | - | Fulham FC | 0:1 (0:1) | ||
| U: 01.04.2010 21:05 | R: 08.04.2010 21:05 | Winnaars: Fulham FC | ||||
| U | Hamburger SV | - | Standard Luik | 2:1 (2:1) | ||
| R | Standard Luik | - | Hamburger SV | 1:3 (1:2) | ||
| U: 01.04.2010 21:05 | R: 08.04.2010 21:05 | Winnaars: Hamburger SV | ||||
| U | Valencia CF | - | Atlético Madrid | 2:2 (0:0) | ||
| R | Atlético Madrid | - | Valencia CF | 0:0 (0:0) | ||
| U: 01.04.2010 21:05 | R: 08.04.2010 21:05 | Winnaars: Atlético Madrid | ||||
| U | SL Benfica | - | Liverpool FC | 2:1 (0:1) | ||
| R | Liverpool FC | - | SL Benfica | 4:1 (2:0) | ||
| U: 01.04.2010 21:05 | R: 08.04.2010 21:05 | Winnaars: Liverpool FC | ||||
